Evidence map›Paper›PMID 27385283›Full record

ArticleMagnetic resonance in medicine2017

Empirical model of human blood transverse relaxation at 3 T improves MRI T

Adam Bush, Matthew Borzage, John Detterich, Roberta M Kato, Herbert J Meiselman, Thomas Coates, John C Wood

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 40 citations in OpenAlex.

  1. Trial
  2. Article
  3. Cerebral Blood Transit in Sickle Cell Anemia.Journal of magnetic resonance imaging : JMRI · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Comparison of cerebral oxygen extraction fraction using ASE and TRUST methods in patients with sickle cell disease and healthy controls.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2024
    Article
  11. Article
  12. Article
  13. Article
  14. TMagnetic resonance in medicine · 2022
    Article
  15. Metabolism of oxygen via TMagnetic resonance in medicine · 2022
    Article
  16. Review
  17. Dependency of RNMR in biomedicine · 2022
    Article
  18. Cardiac MR: From Theory to Practice.Frontiers in cardiovascular medicine · 2022
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Adam BushDivision of Cardiology, Children's Hospital Los Angeles, Los Angeles, California, USA.
Matthew BorzageDivision of Neonatology, Children's Hospital Los Angeles, Los Angeles, California, USA.
John DetterichDivision of Cardiology, Children's Hospital Los Angeles, Los Angeles, California, USA.
Roberta M KatoDivision of Pulmonary, Children's Hospital Los Angeles, Los Angeles, California, USA.
Herbert J MeiselmanDepartment of Physiology and Biophysics, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
Thomas CoatesDivision of Hematology/Oncology, Children's Hospital Los Angeles, Los Angeles, California, USA.
John C WoodDivision of Cardiology, Children's Hospital Los Angeles, Los Angeles, California, USA.
Children's Hospital of Los Angeles · USUniversity of Southern California · US

Funding

Southern California Clinical and Translational Science InstituteUL1TR001855 · NCATS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Thomas A Buchanan, Michele D. Kipke · 2016 to 2026
$81.3M
Neuromodulatory Mechanisms and Regional Autonomic Dysregulation in the Development of Pain in Sickle Cell Disease PatientsU01HL117718 · NHLBI · CHILDREN'S HOSPITAL OF LOS ANGELES · PI COATES, THOMAS DUANE, KHOO, MICHAEL C K · 2013 to 2017
$9.6M
Childrens Hospital Los Angeles Child Health Research Development AwardK12HD052954 · NICHD · CHILDREN'S HOSPITAL OF LOS ANGELES · PI WILLIAMS, ROBERTA GAY · 2006 to 2017
$4.0M
Southern California Clinical and Translational Science InstituteKL2TR000131 · NCATS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI BUCHANAN, THOMAS A · 2012 to 2015
$2.1M
Erythrocyte Nitric Oxide Links Rheology and Vasculopathy in Sickle Cell DiseaseK23HL119627 · NHLBI · CHILDREN'S HOSPITAL OF LOS ANGELES · PI DETTERICH, JON A · 2014 to 2016
$497k
The Impact of Hemoglobin S on Red Blood Cell Nitric Oxide ProductionR03HL138321 · NHLBI · CHILDREN'S HOSPITAL OF LOS ANGELES · PI DETTERICH, JON A · 2017 to 2018
$167k
NCATS NIH HHS KL2 TR000131NCATS NIH HHS UL1 TR001855NHLBI NIH HHS K23 HL119627NHLBI NIH HHS R03 HL138321NHLBI NIH HHS U01 HL117718NICHD NIH HHS K12 HD052954
6 · The paper itself

Abstract

purposeWe sought a human blood T

methodsBlood was drawn from five healthy control subjects. Ninety-three in vitro blood transverse relaxation (T

results1/T

conclusionThis work introduces a robust bilinear calibration model that should be used for MRI oximetry. Magn Reson Med 77:2364-2371, 2017. © 2016 International Society for Magnetic Resonance in Medicine.

Indexed as

Models, CardiovascularComputer SimulationFemaleHumansImage EnhancementImage Interpretation, Computer-AssistedMagnetic Resonance AngiographyMaleMiddle AgedOximetryOxygenReproducibility of ResultsSensitivity and SpecificitySignal Processing, Computer-AssistedOxygenBlood OxygenationBlood RelaxometryT2 Relaxation Under Spin TaggingTransverse Relaxation

Identifiers

PMID27385283
PMCPMC5218988
OpenAlexW2474091774

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.