Evidence map›Paper›PMID 27385039›Full record

ArticleThe British journal of nutrition2016

Dietary intake of manganese and the risk of the metabolic syndrome in a Chinese population.

Biao Zhou, Xuefen Su, Danting Su, Fangfang Zeng, Maggie Haitian Wang, Lichun Huang, Enshan Huang, Yibo Zhu, Dong Zhao, Denghua He and 4 more

Abstract read
In one paragraph

Article in The British journal of nutrition, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  8. Dietary Manganese Modulates Microbiota and Intestinal N-Acylethanolamines in a Sex-Specific Manner in Mice With Diet-Induced Obesity.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
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  16. Consequences of Disturbing Manganese Homeostasis.International journal of molecular sciences · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Biao Zhou1Zhejiang Provincial Centre for Disease Control and Prevention,Hangzhou,Zhejiang 310051,People's Republic of China.
Xuefen Su2School of Public Health and Primary Care, Faculty of Medicine,The Chinese University of Hong Kong,Hong Kong, 999077,People's Republic of China.
Danting Su1Zhejiang Provincial Centre for Disease Control and Prevention,Hangzhou,Zhejiang 310051,People's Republic of China.
Fangfang Zeng2School of Public Health and Primary Care, Faculty of Medicine,The Chinese University of Hong Kong,Hong Kong, 999077,People's Republic of China.
Maggie Haitian Wang2School of Public Health and Primary Care, Faculty of Medicine,The Chinese University of Hong Kong,Hong Kong, 999077,People's Republic of China.
Lichun Huang1Zhejiang Provincial Centre for Disease Control and Prevention,Hangzhou,Zhejiang 310051,People's Republic of China.
Enshan Huang1Zhejiang Provincial Centre for Disease Control and Prevention,Hangzhou,Zhejiang 310051,People's Republic of China.
Yibo Zhu1Zhejiang Provincial Centre for Disease Control and Prevention,Hangzhou,Zhejiang 310051,People's Republic of China.
Dong Zhao1Zhejiang Provincial Centre for Disease Control and Prevention,Hangzhou,Zhejiang 310051,People's Republic of China.
Denghua He4Medical School of Ningbo University,Ningbo,Zhejiang 315211,People's Republic of China.
Xuhui Zhu4Medical School of Ningbo University,Ningbo,Zhejiang 315211,People's Republic of China.
Engkiong Yeoh2School of Public Health and Primary Care, Faculty of Medicine,The Chinese University of Hong Kong,Hong Kong, 999077,People's Republic of China.
Ronghua Zhang1Zhejiang Provincial Centre for Disease Control and Prevention,Hangzhou,Zhejiang 310051,People's Republic of China.
Gangqiang Ding5National Institute for Nutrition and Health,Beijing 100050,People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Animal studies have suggested that Mn might be associated with some components of the metabolic syndrome (MetS). A few epidemiological studies have assessed dietary Mn intake and its association with the risk of the MetS and its components among Chinese adults. In this study, we assessed daily dietary Mn intake and its relationship with MetS risk among Chinese adults in Zhejiang Province using data from the 5th Chinese National Nutrition and Health Survey (2010-2012). A total of 2111 adults were included. Dietary Mn intake was assessed using 3-d 24-h dietary recalls; health-related data were obtained by questionnaire surveys, physical examinations and laboratory assessments. The mean intake of Mn was 6·07 (sd 2·94) mg/d for men (n 998) and 5·13 (sd 2·65) mg/d for women (n 1113). Rice (>42 %) was the main food source of Mn. The prevalence of the MetS was 28·0 % (590/2111). Higher Mn intake was associated with a decreased risk of the MetS in men (Q4 v. Q1 OR 0·62; 95 % CI 0·42, 0·92; P trend=0·043) but an increased risk in women (Q4 v. Q1 OR 1·56; 95 % CI 1·02, 2·45; P trend=0·078). In addition, Mn intake was inversely associated with abdominal obesity (P trend=0·016) and hypertriacylglycerolaemia (P trend=0·029) in men, but positively associated with low HDL-cholesterol in both men (P trend=0·003) and women (P trend<0·001). Our results suggest that higher Mn intakes may be protective against the MetS in men. The inverse association between Mn intake and the MetS in women might be due to the increased risk for low HDL-cholesterol.

Indexed as

Diet SurveysAdultAgedChinaFemaleFood AnalysisHumansMaleManganeseMetabolic SyndromeMiddle AgedRisk FactorsManganeseDietary intakeHDL-cholesterolManganeseMetabolic syndromeMetS metabolic syndromeTAGWC waist circumference

Identifiers

PMID27385039
PMCPMC4983775

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.