ArticleEnvironmental health perspectives2017
Occupational Exposure to Pesticides and the Incidence of Lung Cancer in the Agricultural Health Study.
Article in Environmental health perspectives, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.
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Who cites it
53 citing papers in PubMed, 162 citations in OpenAlex.
- Article
- Research Trends on Pesticide Exposure and Cancer Development: A Global Literature Review (2005-2024).International journal of environmental research and public health · 2026Review
- Phytochemical-Based Strategies for Lung Cancer: Clinical Insights Into Pleiotropic Molecular Signaling and Therapeutic Roles.Phytotherapy research : PTR · 2026Review
- A comprehensive examination of the impact of environmental pollution on lung cancer: A review.Journal of advanced research · 2026Review
- Estimating the half-life of Ethylenethiourea from the urine of garlic farmers in northern Thailand: Characterizing the optimal window for biomonitoring to improve exposure assessment.International journal of hygiene and environmental health · 2026Article
- Risk Factors Associated With Incidence of Lung Cancer in Never-Smokers: A Systematic Review and Meta-Analysis.JTO clinical and research reports · 2025Article
- Article
- Environmental Implication of Herbicide Use.Molecules (Basel, Switzerland) · 2024Review
- Geographical disparities in cancer and occupational exposure to pesticides in a French-West Indies territory (2006-2019).BMC cancer · 2024Article
- Dislodgeable Foliar Residue Measurements and Assessment of Dermal Exposure to Captan for Workers in Apple Orchards.Environmental science & technology · 2024Article
- Exposure to Pesticides and Breast Cancer in an Agricultural Region in Brazil.Environmental science & technology · 2024Article
- Article
- An Updated Evaluation of Atrazine-Cancer Incidence Associations among Pesticide Applicators in the Agricultural Health Study Cohort.Environmental health perspectives · 2024Article
- Differences in suicide acceptability by farming-related occupation, demographic, and religiosity factors, general social survey 2000-2022.PLOS mental health · 2024Article
- Assessment of unintentional acute pesticide poisoning among smallholder vegetable farmers in Trinidad and Jamaica.Frontiers in public health · 2024Article
- Epidemiologic studies of glyphosate and non-Hodgkin's lymphoma: A review with consideration of exposure frequency, systemic dose, and study quality.Global epidemiology · 2023Article
- Review
- Advances in Microfluidics Techniques for Rapid Detection of Pesticide Residues in Food.Foods (Basel, Switzerland) · 2023Review
- Review
- How Does Environmental and Occupational Exposure Contribute to Carcinogenesis in Genitourinary and Lung Cancers?Cancers · 2023Review
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Authors and funding
10 authors at 7 institutions in 1 country.
Funding
Abstract
backgroundOccupational pesticide use is associated with lung cancer in some, but not all, epidemiologic studies. In the Agricultural Health Study (AHS), we previously reported positive associations between several pesticides and lung cancer incidence.
objectiveWe evaluated use of 43 pesticides and 654 lung cancer cases after 10 years of additional follow-up in the AHS, a prospective cohort study comprising 57,310 pesticide applicators from Iowa and North Carolina.
methodsInformation about lifetime pesticide use and other factors was ascertained at enrollment (1993-1997) and updated with a follow-up questionnaire (1999-2005). Cox proportional hazards models were used to calculate hazard ratios (HRs) and 95% confidence intervals (CIs), adjusting for smoking (smoking status and pack-years), sex, and lifetime days of use of any pesticides.
resultsHazard ratios were elevated in the highest exposure category of lifetime days of use for pendimethalin (1.50; 95% CI: 0.98, 2.31), dieldrin (1.93; 95% CI: 0.70, 5.30), and chlorimuron ethyl (1.74; 95% CI: 1.02, 2.96), although monotonic exposure-response gradients were not evident. The HRs for intensity-weighted lifetime days of use of these pesticides were similar. For parathion, the trend was statistically significant for intensity-weighted lifetime days (
conclusionsThese analyses provide additional evidence for an association between pendimethalin, dieldrin, and parathion use and lung cancer risk. We found an association between chlorimuron ethyl, a herbicide introduced in 1986, and lung cancer that has not been previously reported. Continued follow-up is warranted.
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