Evidence map›Paper›PMID 27384573›Full record

ArticleInternational journal of environmental research and public health2016

Sugar-Sweetened Beverage Consumption Is Adversely Associated with Childhood Attention Deficit/Hyperactivity Disorder.

Ching-Jung Yu, Jung-Chieh Du, Hsien-Chih Chiou, Chun-Cheng Feng, Ming-Yi Chung, Winnie Yang, Ying-Sheue Chen, Ling-Chu Chien, Betau Hwang, Mei-Lien Chen

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04165304 (Impact on Drinking Behaviour in Sixth-grade Students Through Changing the School Environment), which is not on this map. Cited by 27 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 7 pooled it
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04165304 naterminatednot on this mapstarted 2019, after this paper: background citation

Impact on Drinking Behaviour in Sixth-grade Students Through Changing the School Environment

TypeinterventionalSponsorSpecial Institute for Preventive Cardiology And NutritionRan2019 to 2020Enrolled431ConditionsStudents of the 6. GradeArmssugar reduction
3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 7 syntheses or guidelines pooled it, 68 citations in OpenAlex.

  1. Pooled it
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  6. Pooled it
  7. The Association between Lead and Attention-Deficit/Hyperactivity Disorder: A Systematic Review.International journal of environmental research and public health · 2019
    Pooled it
  8. Article
  9. Review
  10. Association between free sugars intake and early psychopathological problems.Journal of child health care : for professionals working with children in the hospital and community · 2024
    Article
  11. Article
  12. Nutritional Criminology: Why the Emerging Research on Ultra-Processed Food Matters to Health and Justice.International journal of environmental research and public health · 2024
    Article
  13. Article
  14. Article
  15. Article
  16. Article
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  18. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Ching-Jung YuInstitute of Environmental and Occupational Health Sciences, School of Medicine, National Yang Ming University, Taipei 11221, Taiwan. d49521001@ym.edu.tw.
Jung-Chieh DuDepartment of Pediatrics, Taipei City Hospital, Zhongxiao Branch, Taipei 11556, Taiwan. DAL82@tpech.gov.tw.
Hsien-Chih ChiouDepartment of Child and Adolescent Psychiatry, Taipei City Hospital, Songde Branch, Taipei 11080, Taiwan. DAF28@tpech.gov.tw.
Chun-Cheng FengInstitute of Environmental and Occupational Health Sciences, School of Medicine, National Yang Ming University, Taipei 11221, Taiwan. ryan.feng@gmail.com.
Ming-Yi ChungDepartment of Life Sciences and Institute of Genome Sciences, National Yang Ming University, Taipei 11221, Taiwan. mychung@ym.edu.tw.
Winnie YangDepartment of Pediatrics, Taipei City Hospital, Yangming Branch, Taipei 11146, Taiwan. DAH06@tpech.gov.tw.
Ying-Sheue ChenDepartment of Psychiatry, Taipei Veterans General Hospital, Taipei 11217, Taiwan. drchen3209@gmail.com.
Ling-Chu ChienSchool of Public Health, Taipei Medical University, Taipei 11031, Taiwan. lcchien@tmu.edu.tw.
Betau HwangDepartment of Pediatrics, Taipei City Hospital, Zhongxiao Branch, Taipei 11556, Taiwan. dan75@tpech.gov.tw.
Mei-Lien ChenInstitute of Environmental and Occupational Health Sciences, School of Medicine, National Yang Ming University, Taipei 11221, Taiwan. mlchen@ym.edu.tw.
Taipei City Hospital · TWNational Yang Ming Chiao Tung University · TWNational Yang Ming Chiao Tung University · TWTaipei Medical University · TWTaipei Veterans General Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Attention deficit/hyperactivity disorder (ADHD) is one of the most common childhood neurobehavioral conditions. Evidence of the negative effects of sugar-sweetened beverages (SSBs) on mental health has not been convincing, although a few studies have found an association between high SSB levels and attention problems in children. This study aimed to test the hypothesis that SSB consumption is associated with ADHD among children. Doctor-diagnosed ADHD cases (n = 173) and non-ADHD controls (n = 159) between age 4 to 15 were recruited. SSB consumption, socio-demographic and lifestyle characteristics of the children, as well as of their mothers' characteristics during pregnancy, were collected using a questionnaire. Blood lead levels and polymorphisms of two commonly verified dopaminergic-related genes (the D4 dopamine receptor gene DRD4 and the dopamine transporter gene DAT1) were also analyzed. There was a dose-response relationship between SSB consumption and ADHD. After covariates were adjusted, children who consumed SSBs at moderate levels and high levels had 1.36 and 3.69 odds, respectively, of having ADHD, compared with those who did not consume SSBs (p for trend < 0.05). Similar results were obtained when females were excluded. Our findings highlighted the adverse correlation between SSB consumption and ADHD and indicated a dose-response effect even after covariates were adjusted.

Indexed as

BeveragesSweetening AgentsAdolescentAttention Deficit Disorder with HyperactivityChildChild, PreschoolDopamine Plasma Membrane Transport ProteinsFemaleHumansLeadMalePolymorphism, GeneticReceptors, Dopamine D4Surveys and QuestionnairesDopamine Plasma Membrane Transport ProteinsDRD4 protein, humanLeadReceptors, Dopamine D4SLC6A3 protein, humanSweetening AgentsADHDartificial food coloringblood lead levelcase-controlchildrengene polymorphismpreservativesugar-sweetened beverage

Identifiers

PMID27384573
PMCPMC4962219
OpenAlexW2474215379

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.