ArticleScientific reports2016
Quantifying mammalian genomic DNA hydroxymethylcytosine content using solid-state nanopores.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Insights to Resistive Pulse Sensing of Microparticle and Biological Cells on Microfluidic Chip.Biosensors · 2025Review
- Article
- Improving the Performance of Selective Solid-State Nanopore Sensing Using a Polyhistidine-Tagged Monovalent Streptavidin.ACS sensors · 2024Article
- Identification and Validation of a m5C RNA Modification-Related Gene Signature for Predicting Prognosis and Immunotherapeutic Efficiency of Gastric Cancer.Journal of oncology · 2023Article
- Solid-state nanopore analysis of human genomic DNA shows unaltered global 5-hydroxymethylcytosine content associated with early-stage breast cancer.Nanomedicine : nanotechnology, biology, and medicine · 2021Article
- TETology: Epigenetic Mastermind in Action.Applied biochemistry and biotechnology · 2021Review
- Direct Detection of Conserved Viral Sequences and Other Nucleic Acid Motifs with Solid-State Nanopores.ACS nano · 2021Article
- Microfluidic epigenomic mapping technologies for precision medicine.Lab on a chip · 2019Review
- Simple and Efficient Room-Temperature Release of Biotinylated Nucleic Acids from Streptavidin and Its Application to Selective Molecular Detection.Analytical chemistry · 2019Article
- Repurposing enzymatic transferase reactions for targeted labeling and analysis of DNA and RNA.Current opinion in biotechnology · 2019Review
- 2'-Deoxy-5-(hydroxymethyl)cytidine: estimation in human cancer cells with a simple chemosensor.RSC advances · 2018Article
- Nondestructive, base-resolution sequencing of 5-hydroxymethylcytosine using a DNA deaminase.Nature biotechnology · 2018Article
- Label-free analysis of physiological hyaluronan size distribution with a solid-state nanopore sensor.Nature communications · 2018Article
- Solid-State Nanopore Analysis of Diverse DNA Base Modifications Using a Modular Enzymatic Labeling Process.Nano letters · 2017Article
- Enrichment methods provide a feasible approach to comprehensive and adequately powered investigations of the brain methylome.Nucleic acids research · 2017Article
- Fast and precise detection of DNA methylation with tetramethylammonium-filled nanopore.Scientific reports · 2017Article
Corrections and comments
- Erratum issued
Authors and funding
4 authors.
Funding
Abstract
5-hydroxymethylcytosine (5 hmC), the oxidized form of 5-methylcytosine (5 mC), is a base modification with emerging importance in biology and disease. However, like most epigenetic elements, it is transparent to many conventional genetic techniques and is thus challenging to probe. Here, we report a rapid solid-state nanopore assay that is capable of resolving 5 hmC with high specificity and sensitivity and demonstrate its utility in assessing global modification abundance in genomic DNA.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.