ArticleJournal of applied oral science : revista FOB
Effect of addition of nano-hydroxyapatite on physico-chemical and antibiofilm properties of calcium silicate cements.
Article in Journal of applied oral science : revista FOB. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 30 citations in OpenAlex.
- Developing anti-inflammatory mineral trioxide aggregate as dental implant crown cement to reduce peri-implantitis incidence.Journal of dental sciences · 2026Article
- The comparison of physicochemical and bioactivity properties of different nanoparticles modified calcium silicate-based cement.BMC oral health · 2025Article
- Investigation of bioactivity, biocompatibility, and antibacterial properties of a hydroxyapatite-enhanced nanocomposite for dental applications.Scientific reports · 2025Article
- The Effects of the Incorporation of Nano-Hydroxyapatite on Physico-Chemical Properties of Calcium-Enriched Mixed Cement.Journal of dentistry (Shiraz, Iran) · 2025Article
- Bioceramics in Endodontics: Limitations and Future Innovations-A Review.Dentistry journal · 2025Review
- In Vitro Bacterial Growth on Titanium Surfaces Treated with Nanosized Hydroxyapatite.Journal of functional biomaterials · 2025Article
- Effect of Zinc Oxide Nanoparticles on Calcium-enriched Mixture Cement: Physical, Chemical, and Mechanical Properties.Iranian endodontic journal · 2025Article
- Application of Nanomaterials in Endodontics.BME frontiers · 2024Review
- Effect of Fluorohydroxyapatite on Biological and Physical Properties of MTA Angelus.TheScientificWorldJournal · 2023Article
- Development and Analysis of a Hydroxyapatite Supplemented Calcium Silicate Cement for Endodontic Treatment.Materials (Basel, Switzerland) · 2022Article
- Portland Cement: An Overview as a Root Repair Material.BioMed research international · 2022Review
- Antimicrobial Activity of Calcium Silicate-Based Dental Materials: A Literature Review.Antibiotics (Basel, Switzerland) · 2021Review
- Pivotal Local Drug Delivery Systems in Endodontics; A Review of Literature.Iranian endodontic journal · 2020Review
- Effect of Adding Nano Size Silica on Setting Time and Porosity of Mineral Trioxide Aggregate.Iranian endodontic journal · 2019Article
- Mineral Trioxide Aggregate-A Review of Properties and Testing Methodologies.Materials (Basel, Switzerland) · 2017Review
- Evaluation of physicochemical properties of root-end filling materials using conventional and Micro-CT tests.Journal of applied oral science : revista FOBArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveMineral Trioxide Aggregate (MTA) is a calcium silicate cement composed of Portland cement (PC) and bismuth oxide. Hydroxyapatite has been incorporated to enhance mechanical and biological properties of dental materials. This study evaluated physicochemical and mechanical properties and antibiofilm activity of MTA and PC associated with zirconium oxide (ZrO2) and hydroxyapatite nanoparticles (HAn). MATERIAL AND
methodsWhite MTA (Angelus, Brazil); PC (70%)+ZrO2 (30%); PC (60%)+ZrO2 (30%)+HAn (10%); PC (50%)+ZrO2 (30%)+HAn (20%) were evaluated. The pH was assessed by a digital pH-meter and solubility by mass loss. Setting time was evaluated by using Gilmore needles. Compressive strength was analyzed by mechanical test. Samples were radiographed alongside an aluminum step wedge to evaluate radiopacity. For the antibiofilm evaluation, materials were placed in direct contact with E. faecalis biofilm induced on dentine blocks. The number of colony-forming units (CFU mL-1) in the remaining biolfilm was evaluated. The results were submitted to ANOVA and the Tukey test, with 5% significance.
resultsThere was no difference in pH levels of PC+ZrO2, PC+ZrO2+HAn (10%) and PC+ZrO2+HAn (20%) (p>0.05) and these cements presented higher pH levels than MTA (p<0.05). The highest solubility was observed in PC+ZrO2+HAn (10%) and PC+ZrO2+HAn (20%) (p<0.05). MTA had the shortest initial setting time (p<0.05). All the materials showed radiopacity higher than 3 mmAl. PC+ZrO2 and MTA had the highest compressive strength (p<0.05). Materials did not completely neutralize the bacterial biofilm, but the association with HAn provided greater bacterial reduction than MTA and PC+ZrO2 (p<0.05) after the post-manipulation period of 2 days.
conclusionsThe addition of HAn to PC associated with ZrO2 harmed the compressive strength and solubility. On the other hand, HAn did not change the pH and the initial setting time, but improved the radiopacity (HAn 10%), the final setting time and the E. faecalis antibiofilm activity of the cement.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.