Evidence map›Paper›PMID 27382622›Full record

ReviewInternational scholarly research notices2014

Juvenile Hormone Biosynthesis in Insects: What Is New, What Do We Know, and What Questions Remain?

Fernando G Noriega

Abstract readReview
In one paragraph

Review in International scholarly research notices, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Endocrine gland growth as the developmental switch for insect diapause.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  5. Article
  6. Single-cell transcriptomics of theProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  7. Article
  8. Dietary Lipids and Their Metabolism in the Midgut.Advances in experimental medicine and biology · 2026
    Review
  9. Two cytochrome P450 epoxidases mediate juvenile hormone biosynthesis inbioRxiv : the preprint server for biology · 2025
    Article
  10. Hedgehog and Drosophila germ cell migration.Development (Cambridge, England) · 2025
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. The PBAP chromatin remodeling complex mediates summer diapause via H3K4me3-driven juvenile hormone regulation inProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  16. Article
  17. UnveilingFrontiers in cellular and infection microbiology · 2025
    Article
  18. Review
  19. Chronologically inappropriate morphogenesis (Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  20. Article

5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Fernando G NoriegaDepartment of Biological Sciences, Florida International University, Miami, FL 33199, USA.

Funding

Regulation of juvenile hormone titers in mosquitoesR01AI045545 · NIAID · UNIVERSITY OF ARIZONA · PI NORIEGA, FERNANDO GABRIEL. · 2001 to 2019
$7.1M
NIAID NIH HHS R01 AI045545
6 · The paper itself

Abstract

Our understanding of JH biosynthesis has significantly changed in the last years. In this review I would like to discuss the following topics: (1) the progresses in understanding the JH biosynthesis pathway. Access to genome sequences has facilitated the identification of all the genes encoding biosynthetic enzymes and the completion of comprehensive transcriptional studies, as well as the expression and characterization of recombinant enzymes. Now the existence of different flux directionalites, feed-back loops and pathway branching points in the JH biosynthesis pathways can be explored; (2) the new concepts in the modulation of JH synthesis by allatoregulators. The list of putative JH modulators is increasing. I will discuss their possible role during the different physiological states of the CA; (3) the new theoretical and physiological frameworks for JH synthesis analysis. I will discuss the bases of the flux model for JH biosynthesis. JH plays multiple roles in the control of ovary development in female mosquitoes; therefore, the CA presents different physiological states, where JH synthesis is altered by gating the flux at distinctive points in the pathway; (4) in the final section I will identify new challenges and future directions on JH synthesis research.

Identifiers

PMID27382622
PMCPMC4897325

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.