Evidence map›Paper›PMID 27382533›Full record

ArticleJournal of International Society of Preventive & Community Dentistry

Comparative evaluation of antimicrobial effect of herbal root canal irrigants (Morinda citrifolia, Azadirachta indica, Aloe vera) with sodium hypochlorite: An in vitro study.

Prashant Babaji, Kiran Jagtap, Himani Lau, Nandita Bansal, S Thajuraj, Priti Sondhi

Abstract read
In one paragraph

Article in Journal of International Society of Preventive & Community Dentistry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Antimicrobial Effect of Cinnamaldehyde andInternational journal of microbiology · 2025
    Article
  7. Antimicrobial efficacy of 2% chlorhexidine gel, triphala, andJournal of conservative dentistry and endodontics · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Anti-bacterial efficacy of Aloe vera againstThe Saudi dental journal · 2023
    Review
  12. Article
  13. Comparison of Herbal Agents with Sodium Hypochlorite as Root Canal Irrigant: A Systematic Review ofEvidence-based complementary and alternative medicine : eCAM · 2021
    Review
  14. Antibacterial and Cytotoxic Effects ofInternational journal of dentistry · 2018
    Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Prashant BabajiDepartment of Pedodontics and Preventive Dentistry, Sharavthi Dental College, Karnataka, India.
Kiran JagtapDepartment of Oral Pathology and Microbiology, SMBT Institute of Dental Sciences and Research, Nashik, Maharashtra, India.
Himani LauDepartment of Conservative Dentistry and Endodontics, ITS Dental College, Ghaziyabad, Uttar Pradesh, India.
Nandita BansalDepartment of Conservative Dentistry and Endodontics, DY Patil Dental School, Pune, Maharashtra, India.
S ThajurajDepartment of Conservative Dentistry and Endodontics, PSM College of Dental Science and Research, Kerala, India.
Priti SondhiDepartment of Pedodontics and Preventive Dentistry, Maitri College of Dentistry and Research Centre, Chhattisgarh, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

AIM AND

objectivesSuccessful root canal treatment involves the complete elimination of microorganism from the root canal and the three-dimensional obturation of the canal space. Enterococcus faecalis is the most commonly found bacteria in failed root canal. Chemical irrigation of canals along with biomechanical preparation helps in the elimination of microorganisms. The present study was aimed to evaluate the antimicrobial effect of herbal root canal irrigants (Morinda citrifolia, Azadirachta indica extract, Aloe vera) with sodium hypochlorite (NaOCl). MATERIALS AND

methodsThe bacterial E. faecalis (ATCC) culture was grown overnight in brain heart infusion (BHI) broth and inoculated in Mueller-Hinton agar plates. Antibacterial inhibition was assessed using agar well diffusion method. All five study irrigants were added to respective wells in agar plates and incubated at 37°C for 24 h. Bacterial inhibition zone around each well was recorded. Results were tabulated and statistically analyzed using Statistical Package for the Social Sciences software for Windows, version 19.0. (IBM Corp., Armonk, NY.

resultsHighest inhibitory zone against E. faecalis was seen in NaOCl fallowed by M. citrifolia and A. indica extract, and the least by A. vera extract.

conclusionTested herbal medicine (A. indica extract, M. citrifolia, A. vera) showed inhibitory zone against E. faecalis. Hence, these irrigants can be used as root canal irrigating solutions.

Indexed as

Antimicrobialherbalirrigantsroot canalsodium hypochlorite

Identifiers

PMID27382533
PMCPMC4916791

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.