Evidence map›Paper›PMID 27382515›Full record

ArticleAnatomy & cell biology2016

Human nasociliary nerve with special reference to its unique parasympathetic cutaneous innervation.

Fumio Hosaka, Masahito Yamamoto, Kwang Ho Cho, Hyung Suk Jang, Gen Murakami, Shin-Ichi Abe

Open access · bronzeAbstract read
In one paragraph

Article in Anatomy & cell biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact, top 92% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
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  4. The differences in the anatomy of the thoracolumbar and sacral autonomic outflow are quantitative.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Fumio HosakaDivision of Ophthalmology, Iwamizawa Municipal Hospital, Iwamizawa, Japan.
Masahito YamamotoDepartment of Anatomy, Tokyo Dental College, Chiba, Japan.
Kwang Ho ChoDepartment of Neurology, Wonkwang University School of Medicine and Hospital, Institute of Wonkwang Medical Science, Iksan, Korea.
Hyung Suk JangDivision of Physical Therapy, Ongoul Rehabilitation Hospital, Jeonju, Korea.
Gen MurakamiDivision of Internal Medicine, Iwamizawa Kojin-kai Hospital, Iwamizawa, Japan.
Shin-Ichi AbeDepartment of Anatomy, Tokyo Dental College, Chiba, Japan.
Miwa Hospital · JPTokyo Dental College · JPWonkwang University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The frontal nerve is characterized by its great content of sympathetic nerve fibers in contrast to cutaneous branches of the maxillary and mandibular nerves. However, we needed to add information about composite fibers of cutaneous branches of the nasociliary nerve. Using cadaveric specimens from 20 donated cadavers (mean age, 85), we performed immunohistochemistry of tyrosine hydroxylase (TH), neuronal nitric oxide synthase (nNOS), and vasoactive intestinal polypeptide (VIP). The nasocilliary nerve contained abundant nNOS-positive fibers in contrast to few TH- and VIP-positive fibers. The short ciliary nerves also contained nNOS-positive fibers, but TH-positive fibers were more numerous than nNOS-positive ones. Parasympathetic innervation to the sweat gland is well known, but the original nerve course seemed not to be demonstrated yet. The present study may be the first report on a skin nerve containing abundant nNOS-positive fibers. The unique parasympathetic contents in the nasocilliary nerve seemed to supply the forehead sweat glands as well as glands in the eyelid and nasal epithelium.

Indexed as

Human anatomyImmunohistochemistryNasocialliary nerveNeuronal nitric oxide synthaseSympathetic and parasympathetic nerves

Identifiers

PMID27382515
PMCPMC4927428
OpenAlexW2474219947

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.