Observational studyInternational journal of chronic obstructive pulmonary disease2016
Chronic bronchitis is an independently associated factor for more symptom and high-risk groups.
Observational study in International journal of chronic obstructive pulmonary disease, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- The effect of nebulized N-acetylcysteine on the phlegm of chronic obstructive pulmonary disease: the NEWEST study.BMC pulmonary medicine · 2024Trial
- Impact of bronchitis variability on outcomes of COPD.BMJ open respiratory research · 2025Observational
- Comparing Heterogenous Phenotypes of Chronic Obstructive Pulmonary Disease: Network Analysis and Penalized Generalized Linear Model.International journal of chronic obstructive pulmonary disease · 2025Article
- Clinical significance of chronic bronchitis in different racial groups.BMC pulmonary medicine · 2024Article
- Comparison of clinical characteristics between chronic bronchitis and non-chronic bronchitis in patients with chronic obstructive pulmonary disease.BMC pulmonary medicine · 2022Article
- Diagnosis and Treatment of Early Chronic Obstructive Lung Disease (COPD).Journal of clinical medicine · 2020Review
- CAT Score and SGRQ Definitions of Chronic Bronchitis as an Alternative to the Classical Definition.International journal of chronic obstructive pulmonary disease · 2019Article
- Mixed Phenotype of Emphysema and Airway Wall Thickening Is Associated with Frequent Exacerbation in Chronic Obstructive Pulmonary Disease Patients.International journal of chronic obstructive pulmonary disease · 2019Article
- Different Pattern of Chronic Obstructive Pulmonary Disease Assessment Test Score between Chronic Bronchitis and Non-chronic Bronchitis Patients.Tuberculosis and respiratory diseases · 2018Article
- Alternative definitions of chronic bronchitis and their correlation with CT parameters.International journal of chronic obstructive pulmonary disease · 2018Article
- Clinical phenotypes of COPD and health-related quality of life: a cross-sectional study.International journal of chronic obstructive pulmonary diseaseArticle
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10 authors.
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Abstract
backgroundThe chronic bronchitis (CB) phenotype has been associated with poor quality of life and an increased risk of disease in patients with COPD. However, little information exists regarding the relationship between the CB phenotype and the COPD assessment test (CAT) score. The goal of this study was to reveal the different pattern of CAT scores between CB and non-CB patients. Moreover, we aimed to investigate whether the CB phenotype is an independently associated factor for more symptom and high-risk groups.
methodsData were obtained from the Korea COPD Subgroup Study cohort recruited from 46 centers in South Korea since April 2012. CB patients were defined as having a chronic cough and sputum for 3 months per year, for a period of 2 consecutive years. We investigated the pattern of CAT and subquestionnaire scores between CB and non-CB patients. We also analyzed the proportion of CB phenotypes in each Global initiative for chronic Obstructive Lung Disease (GOLD) stage. Finally, we performed a logistic regression analysis to identify whether the CB phenotype was an independently associated factor for more symptom and high-risk groups.
resultsOf the 1,106 study patients, 11.5% of patients were found to have a CB phenotype. CB phenotypes were most common in GOLD III (GOLD 2006) and GOLD D (GOLD 2015) stages. CAT scores were significantly higher in CB patients not only in terms of the total score but also for each subquestionnaire. Logistic regression revealed that the CB phenotype is an independently associated factor for more symptom and high-risk groups.
conclusionThe present study revealed that CB patients have higher CAT scores and subquestionnaire results compared to non-CB patients. Additionally, we demonstrated that the CB phenotype is an independently associated factor for both more symptom and high-risk groups.
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