Evidence map›Paper›PMID 27382016›Full record

ArticleBMJ case reports2016

Burning mouth syndrome associated with varicella zoster virus.

Maria A Nagel, Don Gilden

Abstract readCase Reports
In one paragraph

Article in BMJ case reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Varicella zoster virus infection.Nature reviews. Disease primers · 2026
    Review
  2. The alpha-herpesviridae in dermatology : Herpes simplex virus types I and II.Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete · 2017
    Review
  3. The alpha-herpesviridae in dermatology : Varicella zoster virus.Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete · 2017
    Review
  4. [The alpha-herpesviridae in dermatology : Herpes simplex virus types I and II. German version].Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete · 2017
    Review
  5. [The alpha-herpesviridae in dermatology : Varicella zoster virus. German version].Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Maria A NagelDepartment of Neurology, University of Colorado School of Medicine, Aurora, Colorado, USA.
Don GildenDepartment of Neurology, University of Colorado School of Medicine, Aurora, Colorado, USA.
University of Colorado Denver · US

Funding

VARICELLA ZOSTER VIRUS VASCULOPATHY: CHANGING CLINICAL PRACTICEP01AG032958 · NIA · UNIVERSITY OF COLORADO DENVER · PI COHRS, RANDALL J. · 2009 to 2023
$30.3M
Purinergic Signaling in Varicella Zoster Virus VasculopathyR01NS094758 · NINDS · UNIVERSITY OF COLORADO DENVER · PI NAGEL, MARIA ACENA · 2015 to 2018
$1.4M
NIA NIH HHS P01 AG032958NINDS NIH HHS R01 NS094758
6 · The paper itself

Abstract

We present two cases of burning mouth syndrome (BMS)-of 8-month duration in a 61-year-old woman and of 2-year duration in a 63-year-old woman-both associated with increased levels of antivaricella zoster virus (VZV) IgM antibodies in serum and with pain that improved with antiviral treatment. Combined with our previous finding of BMS due to herpes simplex virus type 1 (HSV-1) infection, we recommend evaluation of patients with BMS not only for VZV or HSV-1 DNA in the saliva, but also for serum anti-VZV and anti-HSV-1 IgM antibodies. Both infections are treatable with oral antiviral agents.

Indexed as

Antibodies, ViralAntiviral AgentsBurning Mouth SyndromeFemaleHerpes ZosterHumansMiddle AgedSalivaAntibodies, ViralAntiviral Agents

Identifiers

PMID27382016
PMCPMC4956955
OpenAlexW2463046286

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.