Evidence map›Paper›PMID 27381729›Full record

ArticleJournal of Zhejiang University. Science. B2016

A pilot study on using chlorine dioxide gas for disinfection of gastrointestinal endoscopes.

Ying Yi, Li-Mei Hao, Shu-Ren Ma, Jin-Hui Wu, Tao Wang, Song Lin, Zong-Xing Zhang, Jian-Cheng Qi

Open access · hybridAbstract read
In one paragraph

Article in Journal of Zhejiang University. Science. B, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Ying YiInstitute of Medical Equipment, Academy of Military Medical Sciences, Tianjin 300161, China.
Li-Mei HaoInstitute of Medical Equipment, Academy of Military Medical Sciences, Tianjin 300161, China.
Shu-Ren MaDepartment of Digestive Endoscopy, General Hospital of Shenyang Military Region, Shenyang 110840, China.
Jin-Hui WuInstitute of Medical Equipment, Academy of Military Medical Sciences, Tianjin 300161, China.
Tao WangInstitute of Medical Equipment, Academy of Military Medical Sciences, Tianjin 300161, China.
Song LinInstitute of Medical Equipment, Academy of Military Medical Sciences, Tianjin 300161, China.
Zong-Xing ZhangInstitute of Medical Equipment, Academy of Military Medical Sciences, Tianjin 300161, China.
Jian-Cheng QiInstitute of Medical Equipment, Academy of Military Medical Sciences, Tianjin 300161, China.
Academy of Military Medical Sciences · CNGeneral Hospital of Shenyang Military Region · CN

Funding

A Stage I Study of Computer Based Training in CBT for Alcohol Use DisordersR21AA021405 · NIAAA · YALE UNIVERSITY · PI CARROLL, KATHLEEN M. · 2012 to 2013
$358k
NIAAA NIH HHS R21 AA021405
6 · The paper itself

Abstract

objectivesThis pilot study of employing chlorine dioxide (CD) gas to disinfect gastrointestinal endoscopes was conducted to meet the expectations of many endoscopy units in China for a high-efficiency and low-cost disinfectant.

methodsAn experimental prototype with an active circulation mode was designed to use CD gas to disinfect gastrointestinal endoscopes. One type of testing device composed of polytetrafluoroethylene (PTFE) tubes (2 m long, inner diameter 1 mm) and bacterial carrier containers was used to simulate the channel of the endoscope. PTFE bacterial carriers inoculated with Bacillus atrophaeus with or without organic burden were used to evaluate the sporicidal activity of CD gas. Factors including exposure dosage, relative humidity (RH), and flow rate (FR) influencing the disinfection effect of CD gas were investigated. Moreover, an autoptic disinfecting test on eight real gastrointestinal endoscopes after clinical use was performed using the experimental prototype.

resultsRH, exposure dosage, organic burden, and the FR through the channel significantly (P<0.05) affected the disinfection efficacy of CD gas for a long and narrow lumen. The log reduction increased as FR decreased. Treatment with 4 mg/L CD gas for 30 min at 0.8 L/min FR and 75% RH, resulted in complete inactivation of spores. Furthermore, all eight endoscopes with a maximum colony-forming unit of 915 were completely disinfected. The cost was only 3 CNY (0.46 USD) for each endoscope.

conclusionsThe methods and results reported in this study could provide a basis for further studies on using CD gas for the disinfection of endoscopes.

Indexed as

Endoscopes, GastrointestinalChlorine CompoundsDisinfectionHumansOxidesPilot ProjectsSpores, BacterialChlorine Compoundschlorine dioxideOxidesBacillus atrophaeusChlorine dioxideGaseous disinfectantGastrointestinal endoscopeLong and narrow channel

Identifiers

PMID27381729
PMCPMC4940628
OpenAlexW2501542764

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.