ArticleScientific reports2016
The genome and transcriptome of Trichormus sp. NMC-1: insights into adaptation to extreme environments on the Qinghai-Tibet Plateau.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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17 citing papers in PubMed, 35 citations in OpenAlex.
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- Genomic Analysis ofJournal of fungi (Basel, Switzerland) · 2025Article
- A chromosome-scale reference genome assembly for Triplophysa lixianensis.Scientific data · 2024Article
- A genome and gene catalog of the aquatic microbiomes of the Tibetan Plateau.Nature communications · 2024Article
- A Chromosome-level Genome Assembly of Wild Castor Provides New Insights into its Adaptive Evolution in Tropical Desert.Genomics, proteomics & bioinformatics · 2022Article
- Comparative chloroplast genome and transcriptome analysis on the ancient genusFrontiers in plant science · 2022Article
- Physiological and Biochemical Adaptations to High Altitude in Tibetan Frogs,Frontiers in physiology · 2022Article
- Transcriptomes ofPlants (Basel, Switzerland) · 2021Article
- Comparative genomic insights into culturable symbiotic cyanobacteria from the water fernMicrobial genomics · 2021Article
- Transcriptomic Analysis ofFrontiers in microbiology · 2020Article
- The Effect of Plant Geographical Location and Developmental Stage on Root-Associated Microbiomes ofFrontiers in microbiology · 2020Article
- De novo sequencing of the transcriptome reveals regulators of the floral transition in Fargesia macclureana (Poaceae).BMC genomics · 2019Article
- The Parallel Molecular Adaptations to the Antarctic Cold Environment in Two Psychrophilic Green Algae.Genome biology and evolution · 2019Article
- Genome ofProceedings of the National Academy of Sciences of the United States of America · 2019Article
- The cyanobacterial metabolite nocuolin a is a natural oxadiazine that triggers apoptosis in human cancer cells.PloS one · 2017Article
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14 authors at 5 institutions in 2 countries.
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Abstract
The Qinghai-Tibet Plateau (QTP) has the highest biodiversity for an extreme environment worldwide, and provides an ideal natural laboratory to study adaptive evolution. In this study, we generated a draft genome sequence of cyanobacteria Trichormus sp. NMC-1 in the QTP and performed whole transcriptome sequencing under low temperature to investigate the genetic mechanism by which T. sp. NMC-1 adapted to the specific environment. Its genome sequence was 5.9 Mb with a G+C content of 39.2% and encompassed a total of 5362 CDS. A phylogenomic tree indicated that this strain belongs to the Trichormus and Anabaena cluster. Genome comparison between T. sp. NMC-1 and six relatives showed that functionally unknown genes occupied a much higher proportion (28.12%) of the T. sp. NMC-1 genome. In addition, functions of specific, significant positively selected, expanded orthogroups, and differentially expressed genes involved in signal transduction, cell wall/membrane biogenesis, secondary metabolite biosynthesis, and energy production and conversion were analyzed to elucidate specific adaptation traits. Further analyses showed that the CheY-like genes, extracellular polysaccharide and mycosporine-like amino acids might play major roles in adaptation to harsh environments. Our findings indicate that sophisticated genetic mechanisms are involved in cyanobacterial adaptation to the extreme environment of the QTP.
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