ArticleParasitology research2016
Vermamoeba vermiformis-Aspergillus fumigatus relationships and comparison with other phagocytic cells.
Article in Parasitology research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 17 citations in OpenAlex.
- Unraveling the interplay between unicellular parasites and bacterial biofilms: Implications for disease persistence and antibiotic resistance.Virulence · 2024Review
- Epidemiology of free-living amoebae in the Philippines: a review and update.Pathogens and global health · 2022Review
- Diversity of Giant Viruses InfectingFrontiers in microbiology · 2022Review
- Polymicrobial interactions involving fungi and their importance for the environment and in human disease.Microbial pathogenesis · 2020Review
- A hidden battle in the dirt: Soil amoebae interactions with Paracoccidioides spp.PLoS neglected tropical diseases · 2019Article
- The 'Amoeboid Predator-Fungal Animal Virulence' Hypothesis.Journal of fungi (Basel, Switzerland) · 2019Review
- Editorial: Amoebae as Host Models to Study the Interaction With Pathogens.Frontiers in cellular and infection microbiology · 2019Article
- Vermamoeba vermiformis: a Free-Living Amoeba of Interest.Microbial ecology · 2018Review
- New insights from molecular phylogenetics of amoebophagous fungi (Zoopagomycota, Zoopagales).Parasitology research · 2018Article
- Exploring Virulence Determinants of Filamentous Fungal Pathogens through Interactions with Soil Amoebae.Frontiers in cellular and infection microbiology · 2017Review
- Occurrence ofIranian journal of parasitologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Free living amoebae (FLA) are protists ubiquitously present in the environment. Aspergillus fumigatus is a mould responsible for severe deep-seated infections, and that can be recovered in the same habitats as the FLA. By conducting coculture experiments and fungal incubation with amoebal supernatants, we report herein that Vermamoeba vermiformis, a FLA present in hospital water systems, promotes filamentation and growth of A. fumigatus. This finding is of particular importance to institutions whose water systems might harbor FLA and could potentially be used by immunocompromised patients. Also, the relationships between V. vermiformis and A. fumigatus were compared to those between this fungus and two other phagocytic cells: Acanthamoeba castellanii, another FLA, and macrophage-like THP-1 cells. After 4 h of coincubation, the percentages of the three phagocytic cell types with adhered conidia were similar, even though the types of receptors between FLA and macrophagic cell seemed different. However, the percentage of THP-1 with internalized conidia was considerably lower (40 %) in comparison with the two other cell types (100 %). Thus, this study revealed that interactions between A. fumigatus and these three phagocytic cell types show similarities, even though it is premature to extrapolate these results to interpret relationships between A. fumigatus and macrophages.
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Registered trials
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