Evidence map›Paper›PMID 27380033›Full record

ArticleSleep & breathing = Schlaf & Atmung2017

Simple obstructive sleep apnea patients without hypertension or diabetes accelerate kidney dysfunction: a population follow-up cohort study from Taiwan.

Yu-Sheng Lin, Pi-Hua Liu, Shi-Wei Lin, Li-Pang Chuang, Wan-Jing Ho, Yu-Ting Chou, Kuo-Chang Juan, Min-Tzu Lo, Pao-Hsien Chu, Ning-Hung Chen

Open access · hybridAbstract read
In one paragraph

Article in Sleep & breathing = Schlaf & Atmung, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 49 citations in OpenAlex.

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  11. Functional outcomes of sleep predict cardiovascular intermediary outcomes and all-cause mortality in patients on incident hemodialysis.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2021
    Article
  12. Article
  13. Review
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  15. Article
  16. Author Response.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2019
    Article
  17. Article
  18. Obstructive sleep apnea and comorbidities: a dangerous liaison.Multidisciplinary respiratory medicine · 2019
    Review
  19. Risk, Severity, and Predictors of Obstructive Sleep Apnea in Hemodialysis and Peritoneal Dialysis Patients.International journal of environmental research and public health · 2018
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Yu-Sheng LinDepartment of Cardiology, Chang Gung Memorial Hospital and Chang Gung University, Taipei, Taiwan.
Pi-Hua LiuClinical Informatics and Medical Statistics Research Center, College of Medicine, Chang Gung University, Taoyuan, Taiwan.
Shi-Wei LinSleep Center, Department of Pulmonary and Critical Care Medicine, Chang Gung Memorial Hospital, No. 123, Dinghu RD., Guishan Township, Taoyuan County, Taiwan, Republic of China.
Li-Pang ChuangSleep Center, Department of Pulmonary and Critical Care Medicine, Chang Gung Memorial Hospital, No. 123, Dinghu RD., Guishan Township, Taoyuan County, Taiwan, Republic of China.
Wan-Jing HoDepartment of Cardiology, Chang Gung Memorial Hospital and Chang Gung University, Taipei, Taiwan.
Yu-Ting ChouSleep Center, Department of Pulmonary and Critical Care Medicine, Chang Gung Memorial Hospital, No. 123, Dinghu RD., Guishan Township, Taoyuan County, Taiwan, Republic of China.
Kuo-Chang JuanDepartment of Nephrology, Chang Gung Memorial Hospital, Taipei, Taiwan.
Min-Tzu LoDepartment of Radiology, University of California, San Diego, USA.
Pao-Hsien ChuDepartment of Cardiology, Chang Gung Memorial Hospital and Chang Gung University, Taipei, Taiwan.
Ning-Hung ChenSleep Center, Department of Pulmonary and Critical Care Medicine, Chang Gung Memorial Hospital, No. 123, Dinghu RD., Guishan Township, Taoyuan County, Taiwan, Republic of China. ninghung@yahoo.com.tw.
Chang Gung Memorial Hospital · TWUniversity of California, San Diego · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundsObstructive sleep apnea (OSA) is common in patients on hemodialysis, but its correlation with chronic kidney disease (CKD) is not clear. We aimed to clarify the relationship between OSA without hypertension or diabetes and incidence of CKD in Taiwan.

methodsThis population-based cohort study consisted of patients with newly diagnosed OSA between 2000 and 2009. The comparison cohort was matched for age, sex, diabetes mellitus, and hypertension. All subjects previously diagnosed with acute or chronic kidney disease were excluded. The primary end point was newly diagnosed CKD.

resultsWe identified 6866 subjects with OSA during the 10-year study period. The median duration until development of CKD in the OSA cohort was 3.2 years, 2.5 months earlier than that in the non-OSA cohort. After exclusion of hypertension and diabetes, 4319 OSA patients was identified and the hazard ratio (HR) of CKD with OSA was 1.37 (95 % confidence interval [CI], 1.05-1.77; p = 0.019). In the subgroup analysis, an increased incidence of CKD in OSA was observed in women (HR, 1.41; 95 % CI, 1.12-1.78; p = 0.0036).

conclusionsThis longitudinal population-based cohort study provides evidence that patients with OSA even without diabetes or hypertension are at higher risk of developing CKD over the next 3 years and nearly 2.5 months earlier than the non-OSA cohort, particularly women.

Indexed as

Kidney Function TestsAcute Kidney InjuryAdultAgedCohort StudiesDiabetes MellitusFemaleFollow-Up StudiesHumansHypertensionIncidenceKidney Failure, ChronicLongitudinal StudiesMaleMiddle AgedRetrospective StudiesDiabetesHypertensionKidney dysfunctionObstructive sleep apnea

Identifiers

PMID27380033
PMCPMC5343077
OpenAlexW2473831791

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.