Evidence map›Paper›PMID 27379895›Full record

ArticleGastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association2017

Proximal gastrectomy with exclusion of no. 3b lesser curvature lymph node dissection could be indicated for patients with advanced upper-third gastric cancer.

Shusuke Haruta, Hisashi Shinohara, Hisahiro Hosogi, Yu Ohkura, Nao Kobayashi, Aya Mizuno, Ryosuke Okamura, Masaki Ueno, Yoshiharu Sakai, Harushi Udagawa

Open access · bronzeAbstract read
PubMed Publisher
In one paragraph

Article in Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 3 pooled it
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 3 syntheses or guidelines pooled it, 44 citations in OpenAlex.

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  6. Current Trends in Gastric Cancer Surgery and Postoperative Care.The Korean journal of helicobacter and upper gastrointestinal research · 2025
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Shusuke HarutaDepartment of Gastroenterological Surgery, Toranomon Hospital, Tokyo, Japan.
Hisashi ShinoharaDepartment of Gastroenterological Surgery, Toranomon Hospital, Tokyo, Japan. shinosug@kuhp.kyoto-u.ac.jp.ORCID http://orcid.org/0000-0002-1397-8046
Hisahiro HosogiDepartment of Surgery, Kyoto University Graduate School of Medicine, 54 Shogoin Kawara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.
Yu OhkuraDepartment of Gastroenterological Surgery, Toranomon Hospital, Tokyo, Japan.
Nao KobayashiDepartment of Gastroenterological Surgery, Toranomon Hospital, Tokyo, Japan.
Aya MizunoDepartment of Gastroenterological Surgery, Toranomon Hospital, Tokyo, Japan.
Ryosuke OkamuraDepartment of Surgery, Kyoto University Graduate School of Medicine, 54 Shogoin Kawara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.
Masaki UenoDepartment of Gastroenterological Surgery, Toranomon Hospital, Tokyo, Japan.
Yoshiharu SakaiDepartment of Surgery, Kyoto University Graduate School of Medicine, 54 Shogoin Kawara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.
Harushi UdagawaDepartment of Gastroenterological Surgery, Toranomon Hospital, Tokyo, Japan.
Toranomon Hospital · JPKyoto University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundProximal gastrectomy has been introduced for early gastric cancer located in the upper third of the stomach, but expansion of its indication to advanced tumors has not been generally accepted in terms of lesser curvature lymph node dissection.

methodsWe reviewed the medical records of 385 patients with tumors in the upper third of the stomach, and the incidence of metastasis and the therapeutic index related to the proximal (no. 3a) and distal (no. 3b) lymph nodes of the lesser curvature were analyzed and compared with those of tumors in the middle third (n = 1093) and lower third (n = 922) of the stomach.

resultsThe no. 3a rate of metastasis from advanced tumors in the upper third of the stomach was significantly higher than that from tumors in the middle third or lower third of the stomach. The no. 3b metastasis rate did not show any significant differences between the three locations, but the therapeutic index of no. 3b lymph nodes in the upper third of the stomach (1.7) was far lower than that in the middle third (7.1) or lower third (7.0). Further, the rate of metastasis from tumors with the distal border ending in the upper third of the stomach (2.2 %) was significantly (P < 0.0001) lower than that from tumors located in the upper third of the stomach but extending to the middle third (19.6 %), as well as from tumors located in middle third (17.1 %) or lower third (19.6 %), with the therapeutic index being only 1.1. The four no.-3b-positive tumors all measured more than 40 mm, and included one T3 tumor and three T4 tumors.

conclusionProximal gastrectomy with exclusion of no. 3b lymphadenectomy could be indicated for at least T2 tumors measuring less than 40 mm localized in the upper third of the stomach.

Indexed as

FemaleGastrectomyHumansLymph Node ExcisionLymph NodesMaleRetrospective StudiesStomach NeoplasmsSurvival AnalysisLesser curvature lymph nodesLymphadenectomyProximal gastrectomyRight gastric arteryUpper-third gastric cancer

Identifiers

PMID27379895
OpenAlexW2467213143

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.