Evidence map›Paper›PMID 27379824›Full record

ArticleHormone research in paediatrics2017

A Subtrochanteric Femoral Stress Fracture following Bisphosphonate Treatment in an Adolescent Girl.

Alison M Boyce, Michael T Collins, Laura L Tosi, Rachel I Gafni

Open access · bronzeAbstract read
In one paragraph

Article in Hormone research in paediatrics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Bisphosphonate use in children with cerebral palsy.The Cochrane database of systematic reviews · 2021
    Pooled it
  2. Article
  3. Article
  4. Intravenous bisphosphonate therapy in children with spinal muscular atrophy.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2020
    Article
  5. Bisphosphonate Withdrawal: Effects on Bone Formation and Bone Resorption in Maturing Male Mice.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Alison M BoyceSection on Skeletal Disorders and Mineral Homeostasis, Craniofacial and Skeletal Diseases Branch, NIDCR, NIH, Bethesda, Md., USA.
Michael T Collins
Laura L Tosi
Rachel I Gafni
National Institute of Dental and Craniofacial Research · US

Funding

Skeletal Disorders and Mineral Homeostasis SectionZIADE000649 · NIDCR · NATIONAL INSTITUTE OF DENTAL & CRANIOFACIAL RESEARCH · PI COLLINS, MICHAEL · 2009 to 2025
$32.8M
Intramural NIH HHS Z99 DE999999
6 · The paper itself

Abstract

Atypical subtrochanteric and diaphyseal femoral fractures (AFFs) have emerged as a potential complication of bisphosphonate treatment in adults. Despite increasing off-label use of bisphosphonates in children and adolescents for a variety of skeletal disorders, there have been no reports of AFFs in children or adolescents outside of the osteogenesis imperfecta population. We present the case of a 16-year-old girl who developed a subtrochanteric femoral stress fracture following pamidronate treatment for idiopathic juvenile osteoporosis.

Indexed as

AdolescentAdultChildDiphosphonatesFemaleFractures, StressHip FracturesHumansOsteoporosisPamidronateDiphosphonatesPamidronate

Identifiers

PMID27379824
PMCPMC5218986
OpenAlexW2239490885

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.