Evidence map›Paper›PMID 27379667›Full record

ArticleInternational archives of occupational and environmental health2016

Current and cumulative night shift work and subclinical atherosclerosis: results of the Gutenberg Health Study.

S Jankowiak, E Backé, F Liebers, A Schulz, J Hegewald, S Garthus-Niegel, M Nübling, S Blankenberg, N Pfeiffer, K J Lackner and 7 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International archives of occupational and environmental health, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 4 syntheses or guidelines pooled it.

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  4. Shift Work and Early Arterial Stiffness: A Systematic Review.International journal of environmental research and public health · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

S JankowiakDivision Work and Health, Federal Institute for Occupational Safety and Health (BAuA), Noeldnerstr. 40-42, 10317, Berlin, Germany.
E BackéDivision Work and Health, Federal Institute for Occupational Safety and Health (BAuA), Noeldnerstr. 40-42, 10317, Berlin, Germany.
F LiebersDivision Work and Health, Federal Institute for Occupational Safety and Health (BAuA), Noeldnerstr. 40-42, 10317, Berlin, Germany.
A SchulzPreventive Cardiology and Preventive Medicine, Department of Medicine 2, University Medical Center Mainz, Johannes Gutenberg University Mainz, Langenbeckstr. 1, 55131, Mainz, Germany.
J HegewaldFaculty of Medicine, Institute and Policlinic of Occupational and Social Medicine, TU Dresden, Fetscherstr. 74, 01307, Dresden, Germany.
S Garthus-NiegelFaculty of Medicine, Institute and Policlinic of Occupational and Social Medicine, TU Dresden, Fetscherstr. 74, 01307, Dresden, Germany.
M NüblingFFAS, Freiburg Research Centre for Occupational and Social Medicine, Bertoldstr. 27, 79098, Freiburg, Germany.
S BlankenbergDepartment of General and Interventional Cardiology, University Heart Center Hamburg, Martinistr. 52, 20251, Hamburg, Germany.
N PfeifferDepartment of Ophthalmology, University Medical Center Mainz, Johannes Gutenberg-Universität Mainz, Langenbeckstr. 1, 55131, Mainz, Germany.
K J LacknerInstitute for Clinical Chemistry and Laboratory Medicine, University Medical Center, Johannes Gutenberg-Universität Mainz, Langenbeckstr. 1, 55131, Mainz, Germany.
M BeutelDepartment of Psychosomatic Medicine and Psychotherapy, University Medical Center Mainz, Johannes Gutenberg-Universität Mainz, Langenbeckstr. 1, 55131, Mainz, Germany.
M BlettnerInstitute of Medical Biostatistics, Epidemiology and Informatics, University Medical Centre, Johannes Gutenberg-Universität Mainz, Obere Zahlbacher Straße 69, 55131, Mainz, Germany.
T MünzelPreventive Cardiology and Preventive Medicine, Department of Medicine 2, University Medical Center Mainz, Johannes Gutenberg University Mainz, Langenbeckstr. 1, 55131, Mainz, Germany.
P S WildPreventive Cardiology and Preventive Medicine, Department of Medicine 2, University Medical Center Mainz, Johannes Gutenberg University Mainz, Langenbeckstr. 1, 55131, Mainz, Germany.
A SeidlerFaculty of Medicine, Institute and Policlinic of Occupational and Social Medicine, TU Dresden, Fetscherstr. 74, 01307, Dresden, Germany.
S LetzelInstitute of Occupational, Social and Environmental Medicine, University Medical Center of the Johannes Gutenberg University Mainz, Obere Zahlbacher Straße 67, 55131, Mainz, Germany.
U LatzaDivision Work and Health, Federal Institute for Occupational Safety and Health (BAuA), Noeldnerstr. 40-42, 10317, Berlin, Germany. latza.ute@baua.bund.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe study examines the association between exposure to current and cumulative night shift work and subclinical parameters of atherosclerosis.

methodsParticipants of a population-based cohort study (the Gutenberg Health Study, N = 15,010) aged 35-64 years were examined at baseline (2007-2012). Investigations included measurements of arterial stiffness, vascular function [reactive hyperaemia (RH) index], and intima media thickness (IMT). Also, a complete job history (including up to 15 periods), occupational exposures, a variety of lifestyle, and dispositional variables were enquired.

resultsNight shift work was performed by 1071 out of 8065 currently employed individuals. The strongest association after adjustment for age, sex, job complexity level, being a manager, overtime work, and noise appeared for more than 660 night shifts within the last 10 years and a significantly increased arterial stiffness of 0.33 m/s. This reflects a 4 % flow velocity increase for individuals with more than 660 night shifts compared to non-night workers. Regarding the entire professional life, night shift workers showed a significantly decreased vascular function by -0.054 RH index points by using the same adjustment. IMT values did not differ statistically from non-night workers. Lifestyle and dispositional factors showed an influence on all used subclinical atherosclerosis parameters.

conclusionsThe cross-sectional results demonstrate an association between night work and detrimental changes in the atherosclerotic process. The association is more pronounced with more years in night shift and is partly explained by lifestyle and dispositional factors. Longitudinal analyses are necessary to confirm the results.

Indexed as

AdultAtherosclerosisCarotid Intima-Media ThicknessCohort StudiesCross-Sectional StudiesFemaleHealth SurveysHumansHyperemiaLife StyleMaleMiddle AgedOccupational DiseasesOccupational ExposureRisk FactorsTime FactorsArterial stiffnessIntima media thicknessNight shift workOccupationPopulation basedVascular function

Identifiers

PMID27379667
PMCPMC5052298

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.