ReviewCurrent opinion in obstetrics & gynecology2016
The urinary microbiota: a paradigm shift for bladder disorders?
Review in Current opinion in obstetrics & gynecology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
32 citing papers in PubMed, 61 citations in OpenAlex.
- Variations in Urinary Microbiota on a Short-Duration Space Mission to the International Space Station.JU open plus · 2026Article
- Microbiome and metabolomics insights into pediatric urinary tract infection: a narrative review.Childhood kidney diseases · 2026Review
- XGBoost-based urinary microbial signatures enable non-invasive diagnosis and prognosis for urothelial carcinoma.BMC microbiology · 2025Article
- Rewriting the urinary tract paradigm: the urobiome as a gatekeeper of host defense.Molecular biology reports · 2025Review
- Investigation of Bladder Microbiota in Female Patients with Overactive Bladder Syndrome.Urology research & practice · 2025Article
- Improving Patient Outcomes While Reducing Empirical Treatment with Multiplex-Polymerase-Chain-Reaction/Pooled-Antibiotic-Susceptibility-Testing Assay for Complicated and Recurrent Urinary Tract Infections.Diagnostics (Basel, Switzerland) · 2023Article
- Emerging role of the host microbiome in neuropsychiatric disorders: overview and future directions.Molecular psychiatry · 2023Review
- An Overview of the Microbiota of the Human Urinary Tract in Health and Disease: Current Issues and Perspectives.Life (Basel, Switzerland) · 2023Review
- Emerging Non-Antibiotic Options Targeting Uropathogenic Mechanisms for Recurrent Uncomplicated Urinary Tract Infection.International journal of molecular sciences · 2023Review
- The Urinary Microbiome and Bladder Cancer.Life (Basel, Switzerland) · 2023Review
- Clinical relevance of expanded quantitative urine culture in health and disease.Frontiers in cellular and infection microbiology · 2023Review
- Coliphages of the human urinary microbiota.PloS one · 2023Article
- Screen the unforeseen: Microbiome-profiling for detection of zoonotic pathogens in wild rats.Transboundary and emerging diseases · 2022Article
- Characterizing Plasmids in Bacteria Species Relevant to Urinary Health.Microbiology spectrum · 2021Article
- β-Defensin 2, an Antimicrobial Peptide, as a Novel Biomarker for Ulcerative Interstitial Cystitis; Can β-Defensin 2 Suspect the Dysbiosis of Urine Microbiota?Diagnostics (Basel, Switzerland) · 2021Article
- The inflammatory microenvironment and the urinary microbiome in the initiation and progression of bladder cancer.Genes & diseases · 2021Review
- The human urobiome.Mammalian genome : official journal of the International Mammalian Genome Society · 2021Review
- Local induction of bladder Th1 responses to combat urinary tract infections.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Modeling of Urinary Microbiota Associated With Cystitis.Frontiers in cellular and infection microbiology · 2021Article
- A highly polarized TNature immunology · 2020Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
purpose of reviewA resident microbial community [the female urinary microbiota (FUM)] exists within the female bladder of many adult women. Information about the FUM is likely to modify the diagnosis, prevention and treatment of adult women with urinary disorders. This review highlights key findings from recent literature relevant to adult, nonpregnant women. RECENT
findingsSimilar to other human microbial communities, the FUM varies in its characteristics, including organism diversity and predominant organism identity. Recent literature reveals previously undetected organisms and community characteristics that appear associated with certain urinary symptoms, including urinary tract infection and urgency urinary incontinence. The role of individual organisms may range from beneficial to pathogenic and may vary on the basis of an individual's FUM characteristics. The simple dichotomy of 'infected' or 'sterile' no longer sufficiently captures the microbiological complexity of the female bladder. SUMMARY: Deeper understanding of the FUM should yield better methods to restore the microbiota to a healthy state, providing symptom relief. Opportunities to modify the FUM without antibiotic use are exciting possibilities for future research; stand-alone antibiotic use may be reevaluated to improve treatment precision. Long-standing nomenclature for conditions such as asymptomatic bacteriuria and urinary tract infection will likely require modification.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.