Evidence map›Paper›PMID 27379248›Full record

ReviewBioMed research international2016

The Preclinical Research Progress of Stem Cells Therapy in Parkinson's Disease.

Jun Zhang, Xianyun Wang, Jing Li, Rui Huang, Xuerui Yu, Ci Dong, Pujuan Liu, Fan Zhang, Jie Hu, Yixin Qi and 3 more

Open access · hybridAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in BioMed research international, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Jun ZhangCell Therapy Laboratory, The First Hospital of Hebei Medical University, Shijiazhuang, Hebei 050031, China.ORCID 0000-0003-3250-0897
Xianyun WangCell Therapy Laboratory, The First Hospital of Hebei Medical University, Shijiazhuang, Hebei 050031, China.
Jing LiCell Therapy Laboratory, The First Hospital of Hebei Medical University, Shijiazhuang, Hebei 050031, China; Department of Immunology, Basic Medical College, Hebei Medical University, Shijiazhuang, Hebei 050017, China.
Rui HuangDepartment of Paediatrics, The First Hospital of Hebei Medical University, Shijiazhuang, Hebei 050031, China.
Xuerui YuDepartment of General Surgery, The First Hospital of Hebei Medical University, Shijiazhuang, Hebei 050031, China.
Ci DongDepartment of Neurology, The First Hospital of Hebei Medical University, Shijiazhuang, Hebei 050031, China.
Pujuan LiuDepartment of Cardiac Surgery, The First Hospital of Hebei Medical University, Shijiazhuang, Hebei 050031, China.
Fan ZhangCell Therapy Laboratory, The First Hospital of Hebei Medical University, Shijiazhuang, Hebei 050031, China.
Jie HuSchool of Nursing, Hebei Medical University, Shijiazhuang, Hebei, China.
Yixin QiDepartment of Breast Center, The Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Jing ZhangDepartment of Paediatrics, The First Hospital of Hebei Medical University, Shijiazhuang, Hebei 050031, China.
Quanhai LiCell Therapy Laboratory, The First Hospital of Hebei Medical University, Shijiazhuang, Hebei 050031, China; Department of Immunology, Basic Medical College, Hebei Medical University, Shijiazhuang, Hebei 050017, China.ORCID 0000-0003-3629-3856
Baoyong YanCell Therapy Laboratory, The First Hospital of Hebei Medical University, Shijiazhuang, Hebei 050031, China.ORCID 0000-0002-0876-2988
Hebei Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Parkinson's disease (PD) is a type of degenerative disorder of the basal ganglia, causing tremor at rest, muscle rigidity hypokinesia, and dementia. The effectiveness of drug treatments gradually diminishes because the conversion to dopamine within the brain is increasingly disrupted by the progressive degeneration of the dopaminergic terminals. After long-term treatment, most patients with PD suffer from disability that cannot be satisfactorily controlled. To solve these issues, stem cells have recently been used for cell therapy of PD. In this review, the characteristics of different stem cells and their therapeutic effects on PD treatment will be discussed.

Indexed as

Disease Models, AnimalStem Cell ResearchAnimalsBrainHumansParkinson DiseaseStem Cell TransplantationTreatment Outcome

Identifiers

PMID27379248
PMCPMC4917676
OpenAlexW2413774830

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.