Evidence map›Paper›PMID 27379179›Full record

ReviewCilia2016

Eight unique basal bodies in the multi-flagellated diplomonad Giardia lamblia.

Shane G McInally, Scott C Dawson

Open access · hybridAbstract readReview
In one paragraph

Review in Cilia, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.7field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 32 citations in OpenAlex.

  1. Parasitology · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. The compact genome ofMicrobial genomics · 2020
    Article
  9. Article
  10. Microtubule organelles in Giardia.Advances in parasitology · 2020
    Review
  11. Article
  12. Review
  13. Review
  14. Myosin-independent cytokinesis inProceedings of the National Academy of Sciences of the United States of America · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Shane G McInallyDepartment of Microbiology and Molecular Genetics, University of California Davis, One Shields Avenue, Davis, CA 95616 USA.
Scott C DawsonDepartment of Microbiology and Molecular Genetics, University of California Davis, One Shields Avenue, Davis, CA 95616 USA.
University of California, Davis · US

Funding

UC Davis MCB T32 Administrative Supplement to Recognize Excellence in Diversity, Equity, Inclusion, and Accessibility (DEIA) MentorshipT32GM007377 · NIGMS · UNIVERSITY OF CALIFORNIA DAVIS · PI CHEDIN, FREDERIC LOUIS · 1985 to 2023
$9.9M
Molecular mechanisms of attachment by the ventral disc in GiardiaR01AI077571 · NIAID · UNIVERSITY OF CALIFORNIA AT DAVIS · PI DAWSON, SCOTT C · 2009 to 2023
$5.9M
Novel In Vitro and In Vivo Bioluminescent Assays of Giardia Cellular FunctioningR21AI119791 · NIAID · UNIVERSITY OF CALIFORNIA AT DAVIS · PI DAWSON, SCOTT C · 2015 to 2016
$431k
NIAID NIH HHS R01 AI077571NIAID NIH HHS R21 AI119791NIGMS NIH HHS T32 GM007377
6 · The paper itself

Abstract

Giardia lamblia is an intestinal parasitic protist that causes significant acute and chronic diarrheal disease worldwide. Giardia belongs to the diplomonads, a group of protists in the supergroup Excavata. Diplomonads are characterized by eight motile flagella organized into four bilaterally symmetric pairs. Each of the eight Giardia axonemes has a long cytoplasmic region that extends from the centrally located basal body before exiting the cell body as a membrane-bound flagellum. Each basal body is thus unique in its cytological position and its association with different cytoskeletal features, including the ventral disc, axonemes, and extra-axonemal structures. Inheritance of these unique and complex cytoskeletal elements is maintained through basal body migration, duplication, maturation, and their subsequent association with specific spindle poles during cell division. Due to the complex composition and inheritance of specific basal bodies and their associated structures, Giardia may require novel basal body-associated proteins. Thus, protists such as Giardia may represent an undiscovered source of novel basal body-associated proteins. The development of new tools that make Giardia genetically tractable will enable the composition, structure, and function of the eight basal bodies to be more thoroughly explored.

Indexed as

AxonemesBasal bodyFlagellaGiardia lamblia

Identifiers

PMID27379179
PMCPMC4931700
OpenAlexW2345369393

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.