ArticleFrontiers in pharmacology2016
Extracted Triterpenes from Antrodia cinnamomea Reduce the Inflammation to Promote the Wound Healing via the STZ Inducing Hyperglycemia-Diabetes Mice Model.
Article in Frontiers in pharmacology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
13 citing papers in PubMed, 32 citations in OpenAlex.
- Biological Functions and Synthesis of the Active Components inACS omega · 2025Review
- Accelerating wound healing by biomineralizing crystallization formed from ZIF-8/PLA nanofibers with enhanced revascularization and inflammation reduction.Frontiers in bioengineering and biotechnology · 2025Article
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- Recombinantly expressed rhFEB remodeled the skin defect of db/db mice.Applied microbiology and biotechnology · 2024Article
- Extracellular Vesicles from Human Umbilical Cord Mesenchymal Stem Cells Facilitate Diabetic Wound Healing Through MiR-17-5p-mediated Enhancement of Angiogenesis.Stem cell reviews and reports · 2022Article
- Human foreskin-derived dermal stem/progenitor cell-conditioned medium combined with hyaluronic acid promotes extracellular matrix regeneration in diabetic wounds.Stem cell research & therapy · 2021Article
- Tetracyclic and Pentacyclic Triterpenes with High Therapeutic Efficiency in Wound Healing Approaches.Molecules (Basel, Switzerland) · 2020Review
- Protective effect of Gloeostereum incarnatum on ulcerative colitis via modulation of Nrf2/NF‑κB signaling in C57BL/6 mice.Molecular medicine reports · 2020Article
- Human Adipose-Derived Mesenchymal Stem Cells-Derived Exosomal microRNA-19b Promotes the Healing of Skin Wounds Through Modulation of the CCL1/TGF-β Signaling Axis.Clinical, cosmetic and investigational dermatology · 2020Article
- A Pilot Study to Assess Food Safety and Potential Cholesterol-Lowering Efficacy ofEvidence-based complementary and alternative medicine : eCAM · 2020Article
- Cell-free fat extract accelerates diabetic wound healing in db/db mice.American journal of translational research · 2020Article
- Extraction of bioactive ingredients from fruiting bodies ofJournal of food science and technology · 2019Article
- From Inflammation to Current and Alternative Therapies Involved in Wound Healing.International journal of inflammation · 2017Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This research evaluated the effects of triterpenes on the regulation of STZ-induced hyperglycaemic diabetes through an anti-inflammatory response. Diabetic mice were orally administered various concentrations of triterpenes on a daily basis. Weight gain, volume of drinking water, and liver and spleen weight were recorded and evaluated. These evaluations presented a positive regulation to the abnormal metabolism appearance compared to the diabetic mice. In the diabetic mice, the detection of adiponectin production or elevated levels of inflammatory factors such as CCL1 and TPO expression were found to reduce hyperglycaemia and thereby induce an inflammatory response. Moreover, to the best of our knowledge, hyperglycaemia impairs the tissue healing associated with an increased and prolonged inflammatory response. An investigation of the anti-inflammatory response in wound healing as affected by the triterpenes verified the promotion of wound recovery.
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Registered trials
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