ArticleFrontiers in neuroinformatics2016
An Automatic Method for Nucleus Boundary Segmentation Based on a Closed Cubic Spline.
Article in Frontiers in neuroinformatics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- An interactive image segmentation method for the anatomical structures of the main olfactory bulb with micro-level resolution.Frontiers in neuroinformatics · 2023Article
- Automated Brain Region Segmentation for Single Cell Resolution Histological Images Based on Markov Random Field.Neuroinformatics · 2020Article
- Segmental analysis of respiratory liver motion in patients with and without a history of abdominal surgery.Japanese journal of radiology · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The recognition of brain nuclei is the basis for localizing brain functions. Traditional histological research, represented by atlas illustration, achieves the goal of nucleus boundary recognition by manual delineation, but it has become increasingly difficult to extend this handmade method to delineating brain regions and nuclei from large datasets acquired by the recently developed single-cell-resolution imaging techniques for the whole brain. Here, we propose a method based on a closed cubic spline (CCS), which can automatically segment the boundaries of nuclei that differ to a relatively high degree in cell density from the surrounding areas and has been validated on model images and Nissl-stained microimages of mouse brain. It may even be extended to the segmentation of target outlines on MRI or CT images. The proposed method for the automatic extraction of nucleus boundaries would greatly accelerate the illustration of high-resolution brain atlases.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.