Evidence map›Paper›PMID 27378777›Full record

ArticleNucleic acids research2016

Entropic stabilization of folded RNA in crowded solutions measured by SAXS.

Duncan Kilburn, Reza Behrouzi, Hui-Ting Lee, Krishnarjun Sarkar, Robert M Briber, Sarah A Woodson

Open access · goldAbstract read
In one paragraph

Article in Nucleic acids research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 22 citations in OpenAlex.

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  5. Encapsulation of ribozymes inside model protocells leads to faster evolutionary adaptation.Proceedings of the National Academy of Sciences of the United States of America · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Duncan KilburnT. C. Jenkins Department of Biophysics, Johns Hopkins University, Baltimore, MD 21218, USA.
Reza BehrouziT. C. Jenkins Department of Biophysics, Johns Hopkins University, Baltimore, MD 21218, USA.
Hui-Ting LeeT. C. Jenkins Department of Biophysics, Johns Hopkins University, Baltimore, MD 21218, USA.
Krishnarjun SarkarT. C. Jenkins Department of Biophysics, Johns Hopkins University, Baltimore, MD 21218, USA.
Robert M BriberDepartment of Materials Science and Engineering, University of Maryland, College Park, MD 20742, USA rbriber@umd.edu.
Sarah A WoodsonT. C. Jenkins Department of Biophysics, Johns Hopkins University, Baltimore, MD 21218, USA swoodson@jhu.edu.
Johns Hopkins University · USUniversity of Maryland, College Park · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-coding RNAs must fold into specific structures that are stabilized by metal ions and other co-solutes in the cell's interior. Large crowder molecules such as PEG stabilize a bacterial group I ribozyme so that the RNA folds in low Mg

Indexed as

Nucleic Acid ConformationRNA FoldingScattering, Small AngleX-Ray DiffractionAzoarcusEntropyMagnesium ChlorideNucleotidesPolyethylene GlycolsRNARNA, BacterialSolutionsTemperatureThermodynamicsMagnesium ChlorideNucleotidesPolyethylene GlycolsRNARNA, BacterialSolutions

Identifiers

PMID27378777
PMCPMC5100557
OpenAlexW2474315578

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.