Evidence map›Paper›PMID 27378753›Full record

ArticleThe Journal of allergy and clinical immunology2017

Trends, characteristics, and incidence of anaphylaxis in 2001-2010: A population-based study.

Sangil Lee, Erik P Hess, Christine Lohse, Waqas Gilani, Alanna M Chamberlain, Ronna L Campbell

Open access · greenAbstract read
In one paragraph

Article in The Journal of allergy and clinical immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed
9.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 136 citations in OpenAlex.

  1. Article
  2. Unusual Causes of Food-Induced Anaphylaxis - A Review.Indian dermatology online journal · 2026
    Article
  3. Health inequities in pediatric anaphylaxis: A policy framework and call to action for equitable care from SIAIP allergy prevention commission.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2026
    Review
  4. Lactate in Anaphylaxis: 100 Years On.Sports medicine (Auckland, N.Z.) · 2025
    Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Identifying patients at risk of anaphylaxis.The World Allergy Organization journal · 2024
    Review
  10. Article
  11. Article
  12. Article
  13. Overview of Allergy and Anaphylaxis.Immunology and allergy clinics of North America · 2023
    Review
  14. Recent insights into the mechanisms of anaphylaxis.Current opinion in immunology · 2023
    Review
  15. Review
  16. Review
  17. Article
  18. Sex differences in carcinoid syndrome: A gap to be closed.Reviews in endocrine & metabolic disorders · 2022
    Review
  19. Article
  20. Overview of Allergy and Anaphylaxis.Emergency medicine clinics of North America · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Sangil LeeDepartment of Emergency Medicine, Mayo Clinic Health System, Mankato, Minn. Electronic address: lee.sangil@mayo.edu.
Erik P HessDepartment of Emergency Medicine, Mayo Clinic, Rochester, Minn.
Christine LohseDepartment of Emergency Medicine, Mayo Clinic, Rochester, Minn.
Waqas GilaniDepartment of Emergency Medicine, Mayo Clinic, Rochester, Minn.
Alanna M ChamberlainDepartment of Epidemiology, Mayo Clinic, Rochester, Minn.
Ronna L CampbellDepartment of Emergency Medicine, Mayo Clinic, Rochester, Minn.
Mayo Clinic in Arizona · USMayo Clinic Health System · US

Funding

Mayo Clinic Center for Translational Science ActivitiesUL1TR000135 · NCATS · MAYO CLINIC ROCHESTER · PI KHOSLA, SUNDEEP · 2012 to 2015
$41.2M
Rochester Epidemiology ProjectR01AG034676 · NIA · MAYO CLINIC ROCHESTER · PI ROCCA, WALTER A, ST SAUVER, JENNIFER LYNN · 2010 to 2019
$9.5M
ROCHESTER EPIDEMIOLOGY PROJECTR01AR030582 · NIAMS · MAYO CLINIC ROCHESTER · PI ROCCA, WALTER A · 1986 to 2009
$5.1M
NCATS NIH HHS UL1 TR000135NIAMS NIH HHS R01 AR030582NIA NIH HHS R01 AG034676
6 · The paper itself

Abstract

backgroundAnaphylaxis is a potentially life-threatening systemic allergic reaction.

objectiveWe aimed to determine the incidence rate and causes of anaphylaxis during a 10-year period in Olmsted County, Minnesota.

methodsUsing the resources of the Rochester Epidemiology Project, a comprehensive records linkage system, we performed a population-based incidence study in Olmsted County, Minnesota, from 2001 through 2010. All cases with a diagnosis of anaphylactic shock and 20% of cases with related diagnoses were manually reviewed. The relationships of age group, sex, and year of anaphylaxis with incidence rates were assessed by fitting Poisson regression models.

resultsSix hundred thirty-one cases of anaphylaxis were identified. The median age was 31 years (interquartile range, 19-44 years). The overall age- and sex-adjusted incidence rate was 42 (95% CI, 38.7-45.3) per 100,000 person-years. There was a significant increase in the overall incidence of anaphylaxis during the study period, with an average increase of 4.3% per year (P < .001). In addition, there was a 9.8% increase per year in the incidence rate of food-related anaphylaxis. Food-related anaphylaxis was most common in children aged 0 to 9 years, venom-related anaphylaxis was most common in those 20 to 39 years of age, and medication-related anaphylaxis was most common in those 30 to 39 years of age.

conclusionThe overall incidence rate of anaphylaxis was 42 per 100,000 person-years from 2001-2010 in Olmsted County, Minnesota. The incidence of anaphylaxis increased over time, and several inciting triggers were uniquely associated with different age groups.

Indexed as

AdolescentAdultAnaphylaxisChildChild, PreschoolDrug HypersensitivityFemaleFood HypersensitivityHumansIncidenceInfantInfant, NewbornMaleMiddle AgedMinnesotaVenomsVenomsAnaphylaxisepidemiologyfood allergyincidence ratemedication allergyvenom allergy

Identifiers

PMID27378753
PMCPMC5182191
OpenAlexW2413746829

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.