ArticleBMC medical informatics and decision making2016
Pupil diameter changes reflect difficulty and diagnostic accuracy during medical image interpretation.
Article in BMC medical informatics and decision making, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Toward uncertainty-aware manual delineation of brain tumours using eye-tracking and image-derived features.Physics and imaging in radiation oncology · 2026Article
- Associations Between Eye-Movement Patterns, Pupil Dynamics, and the Interpretation of a Single Mixed-Dentition Panoramic Radiograph Among Dental Students: An Exploratory Eye-Tracking Study.Vision (Basel, Switzerland) · 2026Article
- Physicians' eye-tracking in neonatal intensive care: evaluating a mechanical ventilator panel.Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo · 2026Article
- Eye tracking in digital pathology: A comprehensive literature review.Journal of pathology informatics · 2024Review
- Changes in Radiologists' Gaze Patterns Against Lung X-rays with Different Abnormalities: a Randomized Experiment.Journal of digital imaging · 2023Article
- Pathologist pupil dilation reflects experience level and difficulty in diagnosing medical images.Journal of medical imaging (Bellingham, Wash.) · 2023Article
- A time slice analysis of dentistry students' visual search strategies and pupil dilation during diagnosing radiographs.PloS one · 2023Article
- Zoom behavior during visual search modulates pupil diameter and reflects adaptive control states.PloS one · 2023Article
- REFLACX, a dataset of reports and eye-tracking data for localization of abnormalities in chest x-rays.Scientific data · 2022Article
- Article
- What do we know about volumetric medical image interpretation?: a review of the basic science and medical image perception literatures.Cognitive research: principles and implications · 2019Review
- What most captures the physician's interest when evaluating a multiparameter monitor in a Neonatal ICU? - A simulation study.Jornal de pediatriaArticle
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
backgroundNo automated methods exist to objectively monitor and evaluate the diagnostic process while physicians review computerized medical images. The present study tested whether using eye tracking to monitor tonic and phasic pupil dynamics may prove valuable in tracking interpretive difficulty and predicting diagnostic accuracy.
methodsPathologists interpreted digitized breast biopsies varying in diagnosis and rated difficulty, while pupil diameter was monitored. Tonic diameter was recorded during the entire duration of interpretation, and phasic diameter was examined when the eyes fixated on a pre-determined diagnostic region during inspection.
resultsTonic pupil diameter was higher with increasing rated difficulty levels of cases. Phasic diameter was interactively influenced by case difficulty and the eventual agreement with consensus diagnosis. More difficult cases produced increases in pupil diameter, but only when the pathologists' diagnoses were ultimately correct. All results were robust after adjusting for the potential impact of screen brightness on pupil diameter.
conclusionsResults contribute new understandings of the diagnostic process, theoretical positions regarding locus coeruleus-norepinephrine system function, and suggest novel approaches to monitoring, evaluating, and guiding medical image interpretation.
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