Evidence map›Paper›PMID 27377679›Full record

ArticlePediatric pulmonology2017

Rural residence, farming environment, and allergic diseases in Argentinean adolescents.

Yueh-Ying Han, Hèctor A Badellino, Erick Forno, Juan C Celedón

Open access · greenAbstract read
In one paragraph

Article in Pediatric pulmonology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Review
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  6. Review
  7. Urban vs rural residency and allergy prevalence among adult women: Iowa Women's Health Study.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2018
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Yueh-Ying HanDivision of Pediatric Pulmonary Medicine, Allergy, and Immunology, Children's Hospital of Pittsburgh of UPMC, University of Pittsburgh, Pittsburgh, Pennsylvania.
Hèctor A BadellinoDepartment of Pediatric Respiratory Medicine, Regional Eastern Clinic, San Francisco, Córdoba, Argentina.
Erick FornoDivision of Pediatric Pulmonary Medicine, Allergy, and Immunology, Children's Hospital of Pittsburgh of UPMC, University of Pittsburgh, Pittsburgh, Pennsylvania.
Juan C CeledónDivision of Pediatric Pulmonary Medicine, Allergy, and Immunology, Children's Hospital of Pittsburgh of UPMC, University of Pittsburgh, Pittsburgh, Pennsylvania.
Children's Hospital of Pittsburgh · USUniversity of Pittsburgh · US

Funding

Molecular Basis of Pediatric DiseaseK12HD052892 · NICHD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI TERENCE S. DERMODY · 2007 to 2026
$6.5M
Epigenetic Variation and Childhood Asthma in Puerto RicansR01HL117191 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CELEDON, JUAN CARLOS · 2013 to 2020
$5.8M
Vitamin D to Prevent Severe Asthma Exacerbations in High-Risk Children - CCCU01HL119952 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CELEDON, JUAN CARLOS · 2015 to 2018
$2.9M
Obesity and Asthma Subphenotypes and Underlying Genetic and Genomic PathwaysK08HL125666 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI FORNO, ERICK · 2015 to 2018
$589k
NHLBI NIH HHS K08 HL125666NHLBI NIH HHS R01 HL117191NHLBI NIH HHS U01 HL119952NICHD NIH HHS K12 HD052892
6 · The paper itself

Abstract

rationaleLittle is known about residence in a rural or farming environment and allergic diseases in Latin America.

methodsCross-sectional study of rural residence and current wheeze, current asthma and current symptoms of allergic rhino-conjunctivitis in 1,804 adolescents (ages 13-14 years) attending 31 schools in urban and rural areas of San Francisco (Córdoba, Argentina). Rural residence was classified as never, previous, and current. Duration of rural residence was categorized as 0, >0 but ≤5 years, and >5 years. Current wheeze, current asthma, and current allergic rhino-conjunctivitis were defined on the basis of responses to an extensively validated questionnaire from the International Study of Asthma and Allergies in Childhood. Logistic regression was used for the multivariable analysis of rural residence and the outcomes of interest.

resultsAfter adjustment for current smoking and other covariates, current rural residence (odds ratio [OR] = 0.15, 95% confidence interval [CI] = 0.03-0.81) and rural residence for >5 years (OR = 0.32, 95%CI = 0.12-0.84) were significantly associated with reduced odds of current wheeze. In a multivariable analysis, current residence in a rural area (OR = 0.52, 95%CI = 0.32-0.86) and rural residence for >5 years (OR = 0.44, 95%CI = 0.26-0.73) were significantly associated with reduced odds of allergic rhino-conjunctivitis. This association was no longer significant after additional adjustment for current residence in a dairy farm, which was significantly associated with reduced odds of allergic rhino-conjunctivitis. Similarly, current regular contact with farm animals was significantly associated with reduced odds of allergic rhino-conjunctivitis.

conclusionsAmong Argentinean adolescents, current rural residence and rural residence for >5 years were associated with reduced odds of current wheeze and allergic rhino-conjunctivitis. These potential protective effects may be explained by a dairy farm environment, including regular contact with farm animals. Pediatr Pulmonol. 2017;52:21-28. © 2016 Wiley Periodicals, Inc.

Indexed as

AgricultureEnvironmentRespiratory SoundsRural PopulationAdolescentArgentinaAsthmaConjunctivitis, AllergicCross-Sectional StudiesFemaleHumansMalePrevalenceRisk FactorsSurveys and QuestionnairesArgentinean adolescentsdairy farmhay feverrural residencewheeze

Identifiers

PMID27377679
PMCPMC5177519
OpenAlexW2463784270

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.