Evidence map›Paper›PMID 27377596›Full record

ArticleImmunology2016

Transnuclear CD8 T cells specific for the immunodominant epitope Gra6 lower acute-phase Toxoplasma gondii burden.

Anna Sanecka, Nagisa Yoshida, Stephanie K Dougan, John Jackson, Nilabh Shastri, Hidde Ploegh, Nicolas Blanchard, Eva-Maria Frickel

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Immunology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. MIC13 ofJournal of parasitology research · 2025
    Article
  2. Review
  3. Article
  4. Bioinformatics analysis of single and multi-hybrid epitopes of GRA-1, GRA-4, GRA-6 and GRA-7 proteins to improve DNA vaccine design againstJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2018
    Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Anna SaneckaHost-Toxoplasma Interaction Laboratory, The Francis Crick Institute, Mill Hill Laboratory, London, UK.
Nagisa YoshidaHost-Toxoplasma Interaction Laboratory, The Francis Crick Institute, Mill Hill Laboratory, London, UK.
Stephanie K DouganWhitehead Institute for Biomedical Research and Massachusetts Institute of Technology, Cambridge, MA, USA.
John JacksonWhitehead Institute for Biomedical Research and Massachusetts Institute of Technology, Cambridge, MA, USA.
Nilabh ShastriDivision of Immunology and Pathogenesis, Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA.
Hidde PloeghWhitehead Institute for Biomedical Research and Massachusetts Institute of Technology, Cambridge, MA, USA.
Nicolas BlanchardINSERM UMR1043, CNRS UMR5282, Université de Toulouse-UPS, Centre de Physiopathologie de Toulouse Purpan (CPTP), Toulouse, France.
Eva-Maria FrickelHost-Toxoplasma Interaction Laboratory, The Francis Crick Institute, Mill Hill Laboratory, London, UK. eva.frickel@crick.ac.uk.
Massachusetts Institute of Technology · USThe Francis Crick Institute · GBCentre National de la Recherche Scientifique · FRUniversity of California, Berkeley · US

Funding

Medical Research Council MC_UP_1202/12NIAID NIH HHS HHSN272201300006C
6 · The paper itself

Abstract

We generated a CD8 T-cell receptor (TCR) transnuclear (TN) mouse specific to the L

Indexed as

Acute DiseaseAdoptive TransferAnimalsAntigens, ProtozoanCD8-Positive T-LymphocytesDisease Models, AnimalDisease ProgressionHistocompatibility Antigens Class IHybridomasImmunodominant EpitopesLymphocyte ActivationMiceMice, Inbred BALB CMice, TransgenicProtozoan ProteinsReceptors, Antigen, T-Cell, alpha-betaAntigens, ProtozoanGRA6 protein, Toxoplasma gondiiHistocompatibility Antigens Class IImmunodominant EpitopesProtozoan ProteinsReceptors, Antigen, T-Cell, alpha-betaantigens/peptides/epitopesparasitic protozoanT cells

Identifiers

PMID27377596
PMCPMC5046057
OpenAlexW2467970726

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.