SynthesisScientific reports2016
The Efficacy and Cost-Effectiveness of Stepped Care Prevention and Treatment for Depressive and/or Anxiety Disorders: A Systematic Review and Meta-Analysis.
Synthesis in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 80 papers, 8 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Prevention of Mental Health Problems Among Persons Without Personal Housing in the Context of the COVID-19 Epidemic: a Randomized Controlled Trial
Evaluation of Blended Stepped-care Mental Well-being Intervention for Adults: A Randomized Controlled Trial
Who cites it
80 citing papers in PubMed, 8 syntheses or guidelines pooled it, 173 citations in OpenAlex.
- Effects of stepped care on depression outcomes in perinatal women: a systematic review and meta-analysis.BMC pregnancy and childbirth · 2026Pooled it
- Stepped-care models for cancer symptom management: a systematic review of efficacy and cost-effectiveness.Journal of the National Cancer Institute · 2026Pooled it
- Enhancing Quality of Life in Symptomatic Paroxysmal Atrial Fibrillation Patients: A Systematic Analysis of Cognitive Behavioral Therapy Interventions.Clinical cardiology · 2024Pooled it
- Systematic review of structured care pathways in major depressive disorder and bipolar disorder.BMC psychiatry · 2023Pooled it
- Nurse-led task-shifting strategies to substitute for mental health specialists in primary care: A systematic review.International journal of nursing practice · 2022Pooled it
- A Systematic Review of Interventions That Integrate Perinatal Mental Health Care Into Routine Maternal Care in Low- and Middle-Income Countries.Frontiers in psychiatry · 2022Pooled it
- Towards Integrated Youth Care: A Systematic Review of Facilitators and Barriers for Professionals.Administration and policy in mental health · 2021Pooled it
- Internet-Delivered Early Interventions for Individuals Exposed to Traumatic Events: Systematic Review.Journal of medical Internet research · 2018Pooled it
- The work and vocational advice intervention for adults in full or part-time employment: a synopsis of the WAVE feasibility study and RCT.Health technology assessment (Winchester, England) · 2026Trial
- Cost-utility analysis of a collaborative and stepped care model in patients with mental disorders in German primary care (the COMET study).BMC psychiatry · 2025Trial
- Lost and not found: randomized controlled trial of cognitive behavioral therapy for weight-loss in patients with chronic kidney disease.Journal of behavioral medicine · 2025Trial
- Incorporating a Stepped Care Approach Into Internet-Based Cognitive Behavioral Therapy for Depression: Randomized Controlled Trial.JMIR mental health · 2024Trial
- Culturally sensitive stepped care for adolescent refugees: efficacy and cost-utility of a multicentric randomized controlled trial.European child & adolescent psychiatry · 2024Trial
- Effectiveness of a mental health stepped-care programme for healthcare workers with psychological distress in crisis settings: a multicentre randomised controlled trial.BMJ mental health · 2023Trial
- Economic evaluation of a Decision Support Tool to guide intensity of mental health care in general practice: the Link-me pragmatic randomised controlled trial.BMC primary care · 2022Trial
- Trial
- Internet-Based Cognitive Behavioral Therapy in Stepped Care for Chronic Fatigue Syndrome: Randomized Noninferiority Trial.Journal of medical Internet research · 2019Trial
- Therapist-Assisted Internet-Based Cognitive Behavioral Therapy Versus Progressive Relaxation in Obsessive-Compulsive Disorder: Randomized Controlled Trial.Journal of medical Internet research · 2018Trial
- Stepped care approach for medial tibiofemoral osteoarthritis (STrEAMline): protocol for a randomised controlled trial.BMJ open · 2017Trial
- Effectiveness of stepped versus usual care for mental health service delivery: a systematic review and meta-analysis.International journal of mental health systems · 2026Article
20 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Stepped care is an increasingly popular treatment model for common mental health disorders, given the large discrepancy between the demand and supply of healthcare service available. In this review, we aim to compare the efficacy and cost-effectiveness of stepped care prevention and treatment with care-as-usual (CAU) or waiting-list control for depressive and/or anxiety disorders. 5 databases were utilized from its earliest available records up until April 2015. 10 randomized controlled trials were included in this review, of which 6 examined stepped care prevention and 4 examined stepped care treatment, specifically including ones regarding depressive and/or anxiety disorders. Only trials with self-help as a treatment component were included. Results showed stepped care treatment revealed a significantly better performance than CAU in reducing anxiety symptoms, and the treatment response rate of anxiety disorders was significantly higher in stepped care treatment than in CAU. No significant difference was found between stepped care prevention/treatment and CAU in preventing anxiety and/or depressive disorders and improving depressive symptoms. In conclusion, stepped care model appeared to be better than CAU in treating anxiety disorders. The model has the potential to reduce the burden on existing resources in mental health and increase the reach and availability of service.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.