ReviewThe British journal of radiology2016
Target margins in radiotherapy of prostate cancer.
Review in The British journal of radiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
36 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effectiveness of rectal displacement devices in managing prostate motion: a systematic review.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2021Pooled it
- Evaluating Image Quality of Cone Beam Computed Tomography Using HyperSight® on the Varian TrueBeam.Annals of biomedical engineering · 2026Article
- Deep learning-based prediction of interfractional anatomic variations in prostate cancer radiotherapy.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2026Article
- Determining the Correlation and Effect of Rectal and Bladder Volume Change in Shift of Planning Target Volume and Calculating Planning Target Volume Margin with Van Herk Formula in Prostate Cancer Tomotherapy.Journal of biomedical physics & engineering · 2026Article
- Automated Assessment of Nondosimetric Aspects of Prostate Radiation Therapy Treatment Quality in a Large Plan Database.Advances in radiation oncology · 2026Article
- Transformer-based prediction of radiotherapy couch shift risk in prostate cancer based on rectal volume.Scientific reports · 2026Article
- Magnetic Resonance Guided Radiation Therapy (MRgRT) Prostate Motion and Margins.Journal of medical radiation sciences · 2026Article
- In vivo rectal dosimeter with MRI marker.PloS one · 2026Article
- Development of a patient-specific cone-beam computed tomography dose optimization model using machine learning in image-guided radiation therapy.Radiological physics and technology · 2025Article
- Online CBCT-based adaptive radiation with reduced PTV margins for prostate cancer: Does reference plan comparison tell the whole story?Clinical and translational radiation oncology · 2025Article
- Article
- Patient-specific prostate segmentation in kilovoltage images for radiation therapy intrafraction monitoring via deep learning.Communications medicine · 2025Article
- Volume change of the prostate during moderately hypo-fractionated radiotherapy assessed by artificial intelligence.Physics and imaging in radiation oncology · 2025Article
- Intrafraction Motion and Margin Assessment for Ethos Online Adaptive Radiotherapy Treatments of the Prostate and Seminal Vesicles.Advances in radiation oncology · 2024Article
- Impact of technological advances in treatment planning, image guidance, and treatment delivery on target margin design for prostate cancer radiotherapy: an updated review.The British journal of radiology · 2024Review
- Optical Surface Management System and BladderScan for Patient Setup During Radiotherapy of Postoperative Prostate Cancer.BioMed research international · 2024Article
- Prostate stereotactic body radiotherapy: quantifying intra-fraction motion and calculating margins using the new BIR geometric uncertainties in daily online IGRT recommendations.The British journal of radiology · 2023Article
- Reducing PTV margins for prostate SBRT with motion compensation and gating techniques.Journal of applied clinical medical physics · 2023Article
- Simulating an intra-fraction adaptive workflow to enable PTV margin reduction in MRIgART volumetric modulated arc therapy for prostate SBRT.Frontiers in oncology · 2023Article
- The role of image-guided radiotherapy in prostate cancer: A systematic review and meta-analysis.Clinical and translational radiation oncology · 2023Review
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We reviewed the literature on the use of margins in radiotherapy of patients with prostate cancer, focusing on different options for image guidance (IG) and technical issues. The search in PubMed database was limited to include studies that involved external beam radiotherapy of the intact prostate. Post-prostatectomy studies, brachytherapy and particle therapy were excluded. Each article was characterized according to the IG strategy used: positioning on external marks using room lasers, bone anatomy and soft tissue match, usage of fiducial markers, electromagnetic tracking and adapted delivery. A lack of uniformity in margin selection among institutions was evident from the review. In general, introduction of pre- and in-treatment IG was associated with smaller planning target volume (PTV) margins, but there was a lack of definitive experimental/clinical studies providing robust information on selection of exact PTV values. In addition, there is a lack of comparative research regarding the cost-benefit ratio of the different strategies: insertion of fiducial markers or electromagnetic transponders facilitates prostate gland localization but at a price of invasive procedure; frequent pre-treatment imaging increases patient in-room time, dose and labour; online plan adaptation should improve radiation delivery accuracy but requires fast and precise computation. Finally, optimal protocols for quality assurance procedures need to be established.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.