Evidence map›Paper›PMID 27377064›Full record

ArticleRetrovirology2016

Retrovirus Integration Database (RID): a public database for retroviral insertion sites into host genomes.

Wei Shao, Jigui Shan, Mary F Kearney, Xiaolin Wu, Frank Maldarelli, John W Mellors, Brian Luke, John M Coffin, Stephen H Hughes

Abstract read
In one paragraph

Article in Retrovirology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed.

  1. Article
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  11. Review
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  18. Observational
  19. Article
  20. Joint profiling of chromatin accessibility and CAR-T integration site analysis at population and single-cell levels.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Wei ShaoAdvanced Biomedical Computing Center, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research (FNLCR), Frederick, MD, USA. shaow@mail.nih.gov.
Jigui ShanAdvanced Biomedical Computing Center, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research (FNLCR), Frederick, MD, USA.
Mary F KearneyHIV Dynamics and Replication Program, NCI, Frederick, MD, USA.
Xiaolin WuLeidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research (FNLCR), Frederick, MD, USA.
Frank MaldarelliHIV Dynamics and Replication Program, NCI, Frederick, MD, USA.
John W MellorsDivision of Infectious Disease, University of Pittsburgh, Pittsburgh, PA, USA.
Brian LukeAdvanced Biomedical Computing Center, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research (FNLCR), Frederick, MD, USA.
John M CoffinDepartment of Molecular Biology and Microbiology, Tufts University, Boston, MA, USA.
Stephen H HughesHIV Dynamics and Replication Program, NCI, Frederick, MD, USA.

Funding

IntegraseZIABC011426 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI HUGHES, STEPHEN H · 2012 to 2022
$14.0M
CCR NIH HHS HHSN261200800001CNCI NIH HHS HHSN261200800001E
6 · The paper itself

Abstract

unlabelledThe NCI Retrovirus Integration Database is a MySql-based relational database created for storing and retrieving comprehensive information about retroviral integration sites, primarily, but not exclusively, HIV-1. The database is accessible to the public for submission or extraction of data originating from experiments aimed at collecting information related to retroviral integration sites including: the site of integration into the host genome, the virus family and subtype, the origin of the sample, gene exons/introns associated with integration, and proviral orientation. Information about the references from which the data were collected is also stored in the database. Tools are built into the website that can be used to map the integration sites to UCSC genome browser, to plot the integration site patterns on a chromosome, and to display provirus LTRs in their inserted genome sequence. The website is robust, user friendly, and allows users to query the database and analyze the data dynamically. AVAILABILITY: https://rid.ncifcrf.gov ; or http://home.ncifcrf.gov/hivdrp/resources.htm .

Indexed as

Databases, GeneticGenome, HumanHIV-1Host-Pathogen InteractionsHumansInternetProvirusesRetroviridaeVirus IntegrationDatabaseExpanded clonesHIVIntegration siteIntegration site assayISARetrovirus

Identifiers

PMID27377064
PMCPMC4932684

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.