Evidence map›Paper›PMID 27376503›Full record

ArticlePathogens and global health2016

Kato-Katz and Lumbreras rapid sedimentation test to evaluate helminth prevalence in the setting of a school-based deworming program.

Martha Lopez, Maria Luisa Morales, Monisha Konana, Paige Hoyer, Roberto Pineda-Reyes, Arthur Clinton White, Hector Hugo Garcia, Andres Guillermo Lescano, Eduardo Gotuzzo, Miguel Mauricio Cabada

Open access · greenAbstract read
In one paragraph

Article in Pathogens and global health, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Martha Lopeza Universidad Peruana Cayetano Heredia and University of Texas Medical Branch Collaborative Research Center , Cusco , Peru.
Maria Luisa Moralesa Universidad Peruana Cayetano Heredia and University of Texas Medical Branch Collaborative Research Center , Cusco , Peru.
Monisha Konanab School of Medicine , University of Texas Medical Branch , Galveston , TX , USA.
Paige Hoyerb School of Medicine , University of Texas Medical Branch , Galveston , TX , USA.
Roberto Pineda-Reyesa Universidad Peruana Cayetano Heredia and University of Texas Medical Branch Collaborative Research Center , Cusco , Peru.
Arthur Clinton Whitea Universidad Peruana Cayetano Heredia and University of Texas Medical Branch Collaborative Research Center , Cusco , Peru.
Hector Hugo Garciad Cysticercosis Working Group in Peru , Lima , Peru.
Andres Guillermo Lescanog School of Public Health and Administration , Universidad Peruana Cayetano Heredia , Lima , Peru.
Eduardo Gotuzzoi Instituto de Medicina Tropical Alexander von Humboldt , Universidad Peruana Cayetano Heredia , Lima , Peru.
Miguel Mauricio Cabadaa Universidad Peruana Cayetano Heredia and University of Texas Medical Branch Collaborative Research Center , Cusco , Peru.
Universidad Peruana Cayetano Heredia · PEThe University of Texas Medical Branch at Galveston · USInstituto Nacional de Enfermedades Neoplásicas · PE

Funding

Peru Infectious Diseases Epidemiology Research Training ConsortiumD43TW007393 · FIC · UNIVERSIDAD PERUANA CAYETANO HEREDIA · PI Andres G Lescano · 2005 to 2026
$5.9M
Impact of Fascioliasis among Children in the Peruvian HighlandsR01AI104820 · NIAID · UNIVERSIDAD PERUANA CAYETANO HEREDIA · PI CABADA, MIGUEL MAURICIO · 2013 to 2017
$659k
FIC NIH HHS D43 TW007393NIAID NIH HHS R01 AI104820Wellcome Trust 091077
6 · The paper itself

Abstract

The sensitivity of the Kato-Katz test is suboptimal for the evaluation of intestinal helminth prevalence. Moreover, during mass deworming, as helminth egg burden decreases, the sensitivity is likely to decrease. The Lumbreras rapid sedimentation (Lumbreras) is a low-cost non-quantitative test, but may provide useful information in low burden areas. We compared the prevalence of intestinal helminth infections assessed by the Kato-Katz and the Lumbreras rapid sedimentation test on 3 stool specimens from each of 1083 children. The sensitivities were compared using the McNemar paired test. Using the combined outcome of the 3 different stool tests as the standard, Kato-Katz had lower sensitivity than Lumbreras rapid sedimentation tests for Ascaris lumbricoides (85.1% vs. 95.1%, p = 0.03), Hymenolepis nana (77.7% vs. 97.9%, p < 0.01), Trichuris trichura (41.7% vs. 100%, p = 0.01), hookworm (0% vs. 100%, p = 0.01), and Strongyloides stercoralis (0% vs. 88%, p < 0.01). Kato-Katz demonstrated significantly lower sensitivity, missing most T. trichiura, hookworm, and S. stercoralis infections. The combination of Kato-Katz and Lumbreras rapid sedimentation tests enables the detection of more intestinal helminths infections in post-deworming low prevalence areas.

Indexed as

Clinical Laboratory TechniquesSchool Health ServicesAnimalsAscaris lumbricoidesChildChild, PreschoolFecesFemaleHelminthiasisHumansIntestinal Diseases, ParasiticMaleParasite Egg CountPrevalenceSchoolsSensitivity and SpecificityKato-KatzLumbreras rapid sedimentationScreening testsSensitivitySoil-transmitted helminths

Identifiers

PMID27376503
PMCPMC4984960
OpenAlexW2462067515

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.