Evidence map›Paper›PMID 27376321›Full record

SynthesisNutrients2016

Dairy Intake Enhances Body Weight and Composition Changes during Energy Restriction in 18-50-Year-Old Adults-A Meta-Analysis of Randomized Controlled Trials.

Welma Stonehouse, Thomas Wycherley, Natalie Luscombe-Marsh, Pennie Taylor, Grant Brinkworth, Malcolm Riley

Open access · goldAbstract readMeta-Analysis
In one paragraph

Synthesis in Nutrients, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 2 pooled it
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 2 syntheses or guidelines pooled it, 57 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Welma StonehouseCommonwealth Scientific Industrial Research Organisation, Adelaide 5000, South Australia, Australia. welma.stonehouse@csiro.au.
Thomas WycherleySchool of Health Sciences, University of South Australia, Adelaide 5000, South Australia, Australia. tom.wycherley@unisa.edu.au.
Natalie Luscombe-MarshCommonwealth Scientific Industrial Research Organisation, Adelaide 5000, South Australia, Australia. natalie.luscombe-marsh@csiro.au.
Pennie TaylorCommonwealth Scientific Industrial Research Organisation, Adelaide 5000, South Australia, Australia. pennie.taylor@csiro.au.
Grant BrinkworthCommonwealth Scientific Industrial Research Organisation, Adelaide 5000, South Australia, Australia. grant.brinkworth@csiro.au.
Malcolm RileyCommonwealth Scientific Industrial Research Organisation, Adelaide 5000, South Australia, Australia. malcolm.riley@csiro.au.
Health Sciences and Nutrition · AUUniversity of South Australia · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimsA meta-analysis of randomized controlled trials (RCTs) was performed to investigate the effects of dairy food or supplements during energy restriction on body weight and composition in 18-50-year-old.

methodsRCTs ≥ 4 weeks comparing the effect of dairy consumption (whole food or supplements) with control diets lower in dairy during energy restriction on body weight, fat and lean mass were identified by searching MEDLINE, EMBASE, Pubmed, Cochrane Central and World Health Organization International Clinical Trials Registry Platform (WHO ICTRP) until March 2016. Reports were identified and critically appraised in duplicate. Data were pooled using random-effects meta-analysis. Chi²- and I²-statistics indicated heterogeneity. Dose effect was assessed using meta-regression analysis. GRADE guidelines were used to rate the quality (QR) of the evidence considering risk of bias, inconsistency, indirectness, imprecision, publication bias and effect estimates.

results27 RCTs were reviewed. Participants consumed between 2 and 4 standard servings/day of dairy food or 20-84 g/day of whey protein compared to low dairy control diets, over a median of 16 weeks. A greater reduction in body weight (-1.16 kg [-1.66, -0.66 kg], p < 0.001, I² = 11%, QR = high, n = 644) and body fat mass (-1.49 kg [-2.06, -0.92 kg], p < 0.001, I² = 21%, n = 521, QR = high) were found in studies largely including women (90% women). These effects were absent in studies that imposed resistance training (QR = low-moderate). Dairy intake resulted in smaller loss of lean mass (all trials pooled: 0.36 kg [0.01, 0.71 kg], p = 0.04, I² = 64%, n = 651, QR = moderate). No between study dose-response effects were seen.

conclusionsIncreased dairy intake as part of energy restricted diets resulted in greater loss in bodyweight and fat mass while attenuating lean mass loss in 18-50-year-old adults. Further research in males is needed to investigate sex effects.

Indexed as

Body WeightCaloric RestrictionDairy ProductsDiet, ReducingAdiposityAdolescentAdultBody CompositionBody Mass IndexEnergy IntakeExerciseFemaleHumansMaleMiddle AgedObesitybody compositionbody fat massbody lean massbody weightdairydairy supplementsenergy restriction

Identifiers

PMID27376321
PMCPMC4963870
OpenAlexW2460546179

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.