ReviewFrontiers in nutrition2016
Increased Hydration Can Be Associated with Weight Loss.
Review in Frontiers in nutrition, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Narrative Review of Hydration and Selected Health Outcomes in the General Population.Nutrients · 2019Pooled it
- The Hormone FGF21 Stimulates Water Drinking in Response to Ketogenic Diet and Alcohol.Cell metabolism · 2018Trial
- Comparative Adaptive Mechanisms of Two Indigenous Goat Genetic Resources Under Simulated Water Scarcity.Animals : an open access journal from MDPI · 2026Article
- A High Dose of Short-term Intraperitoneal D-galactose-induced Aging Process in Male Rats.Annals of African medicine · 2026Article
- Food Intolerance After Bariatric Surgery: A Narrative Review of Prevalence, Mechanisms, and Dietary Management.Nutrients · 2025Review
- Gender and Age-Specific Responses to Non-Invasive Body-Contouring Interventions and Their Impact on Body Composition-Pilot Study.Nutrients · 2025Observational
- Association between water intake and abdominal obesity: the Korea National Health and Nutrition Examination Survey 2019-2021.Korean journal of family medicine · 2025Article
- Associations of water intake and Intra-Meal fluid consumption with obesity, insulin resistance, and predictors of cardiovascular diseases among Iranian women.Scientific reports · 2025Article
- Article
- Article
- Metabolic syndrome: epidemiology, mechanisms, and current therapeutic approaches.Frontiers in nutrition · 2025Review
- Exploring the therapeutic potential ofVeterinary world · 2024Article
- Non-invasive approaches to hydration assessment: a literature review.Urolithiasis · 2024Review
- Water Consumption: Effect on Energy Expenditure and Body Weight Management.Current obesity reports · 2023Review
- The association between hydration status and body composition in healthy children and adolescents.Journal of pediatric endocrinology & metabolism : JPEM · 2023Article
- 'Saba' banana (Current research in food science · 2022Article
- The Association between Healthy Beverage Index and Healthy and Unhealthy Obesity Phenotypes among Obese Women: A Cross-Sectional Study.International journal of clinical practice · 2022Article
- Quantification of body fluid compartmentalization by combined time-domain nuclear magnetic resonance and bioimpedance spectroscopy.American journal of physiology. Regulatory, integrative and comparative physiology · 2021Article
- Fluid Intake Monitoring System Using a Wearable Inertial Sensor for Fluid Intake Management.Sensors (Basel, Switzerland) · 2020Article
- Obesity epidemic in urban Tanzania: a public health calamity in an already overwhelmed and fragmented health system.BMC endocrine disorders · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This mini-review develops the hypothesis that increased hydration leads to body weight loss, mainly through a decrease in feeding, and a loss of fat, through increased lipolysis. The publications cited come from animal, mainly rodent, studies where manipulations of the central and/or the peripheral renin-angiotensin system lead to an increased drinking response and a decrease in body weight. This hypothesis derives from a broader association between chronic hypohydration (extracellular dehydration) and raised levels of the hormone angiotensin II (AngII) associated with many chronic diseases, such as obesity, diabetes, cancer, and cardiovascular disease. Proposed mechanisms to explain these effects involve an increase in metabolism due to hydration expanding cell volume. The results of these animal studies often can be applied to the humans. Human studies are consistent with this hypothesis for weight loss and for reducing the risk factors in the development of obesity and type 2 diabetes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.