ArticleBiomedical optics express2016
Infrared spectroscopic imaging detects chemical modifications in liver fibrosis due to diabetes and disease.
Article in Biomedical optics express, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed.
- Point-of-care detection of fibrosis in liver transplant surgery using near-infrared spectroscopy and machine learning.Health science reports · 2023Article
- Digital Histopathology by Infrared Spectroscopic Imaging.Annual review of analytical chemistry (Palo Alto, Calif.) · 2023Review
- Analysis of Hepatic Fibrosis Characteristics in Cirrhotic Patients with and without Hepatocellular Carcinoma by FTIR Spectral Imaging.Molecules (Basel, Switzerland) · 2020Article
- Mitigating fringing in discrete frequency infrared imaging using time-delayed integration.Biomedical optics express · 2018Article
- Predicting Fibrosis Progression in Renal Transplant Recipients Using Laser-Based Infrared Spectroscopic Imaging.Scientific reports · 2018Article
- Infrared spectroscopic imaging: Label-free biochemical analysis of stroma and tissue fibrosis.The international journal of biochemistry & cell biology · 2017Review
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
The importance of stroma as a rich diagnostic region in tissue biopsies is growing as there is an increasing understanding that disease processes in multiple organs can affect the composition of adjacent connective tissue regions. This may be especially true in the liver, since this organ's central metabolic role exposes it to multiple disease processes. We use quantum cascade laser infrared spectroscopic imaging to study changes in the chemical status of hepatocytes and fibrotic regions of liver tissue that result from the progression of liver cirrhosis to hepatocellular carcinoma and the potentially confounding effects of diabetes mellitus.
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Registered trials
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