ArticleBiomedical optics express2016
In vivo assessment of optical properties of basal cell carcinoma and differentiation of BCC subtypes by high-definition optical coherence tomography.
Article in Biomedical optics express, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 31 citations in OpenAlex.
- ChatGPT, Gemini, and Claude in clinical and dermoscopic image analysis of basal cell carcinoma and its common mimickers: A comparative performance analysis.JID innovations : skin science from molecules to population health · 2026Article
- FDA and EMA-approved noninvasive imaging techniques for basal cell carcinoma subtyping: A systematic review.JAAD international · 2025Review
- Sclerodermiform Cell Epithelioma of the Palpebromalar Region.Plastic and reconstructive surgery. Global open · 2024Article
- Multidimensional quantitative characterization of basal cell carcinoma by spectral- and time-resolved two-photon microscopy.Nanophotonics (Berlin, Germany) · 2024Article
- Cross-Polarization Optical Coherence Tomography for Clinical Evaluation of Dermal Lesion Degrees in Vulvar Lichen Sclerosus.Sovremennye tekhnologii v meditsine · 2023Article
- Fiber-based hand-held RCM-OCT probe for noninvasive assessment of skin lesions and therapy guidance.Translational biophotonics · 2022Article
- Manually scanned single fiber optical coherence tomography for skin cancer characterization.Scientific reports · 2021Article
- The potential utility of integrated reflectance confocal microscopy-optical coherence tomography for guiding triage and therapy of basal cell carcinomas.Journal of Cancer · 2020Article
- The value of ultrahigh resolution OCT in dermatology - delineating the dermo-epidermal junction, capillaries in the dermal papillae and vellus hairs.Biomedical optics express · 2018Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
High-definition optical coherence tomography (HD-OCT) features of basal cell carcinoma (BCC) have recently been defined. We assessed in vivo optical properties (IV-OP) of BCC, by HD-OCT. Moreover their critical values for BCC subtype differentiation were determined. The technique of semi-log plot whereby an exponential function becomes linear has been implemented on HD-OCT signals. The relative attenuation factor (µraf ) at different skin layers could be assessed.. IV-OP of superficial BCC with high diagnostic accuracy (DA) and high negative predictive values (NPV) were (i) decreased µraf in lower part of epidermis and (ii) increased epidermal thickness (E-T). IV-OP of nodular BCC with good to high DA and NPV were (i) less negative µraf in papillary dermis compared to normal adjacent skin and (ii) significantly decreased E-T and papillary dermal thickness (PD-T). In infiltrative BCC (i) high µraf in reticular dermis compared to normal adjacent skin and (ii) presence of peaks and falls in reticular dermis had good DA and high NPV. HD-OCT seems to enable the combination of in vivo morphological analysis of cellular and 3-D micro-architectural structures with IV-OP analysis of BCC. This permits BCC sub-differentiation with higher accuracy than in vivo HD-OCT analysis of morphology alone.
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