ArticleBiomedical optics express2016
Portable, parallel 9-wavelength near-infrared spectral tomography (NIRST) system for efficient characterization of breast cancer within the clinical oncology infusion suite.
Article in Biomedical optics express, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- MRI-Guided Near-Infrared Spectroscopic Tomography (MRg-NIRST) Imaging System With Wearable Breast Optical Interface for Breast Cancer Imaging.IEEE transactions on bio-medical engineering · 2025Article
- Review of recent advances in frequency-domain near-infrared spectroscopy technologies [Invited].Biomedical optics express · 2023Review
- Performance assessment of MRI guided continuous wave near-infrared spectral tomography for breast imaging.Biomedical optics express · 2021Article
- Stable tissue-simulating phantoms with various water and lipid contents for diffuse optical spectroscopy.Biomedical optics express · 2018Article
- Emerging Breast Imaging Technologies on the Horizon.Seminars in ultrasound, CT, and MR · 2018Article
- Collagen quantification in breast tissue using a 12-wavelength near infrared spectral tomography (NIRST) system.Biomedical optics express · 2017Article
- Multimodal breast cancer imaging using coregistered dynamic diffuse optical tomography and digital breast tomosynthesis.Journal of biomedical optics · 2017Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
A portable near-infrared spectral tomography (NIRST) system was developed with simultaneous frequency domain (FD) and continuous-wave (CW) optical measurements for efficient characterization of breast cancer in a clinical oncology setting. Simultaneous FD and CW recordings were implemented to speed up acquisition to 3 minutes for all 9 wavelengths, spanning a range from 661nm to 1064nm. An adjustable interface was designed to fit various breast sizes and shapes. Spatial images of oxy- and deoxy-hemoglobin, water, lipid, and scattering components were reconstructed using a 2D FEM approach. The system was tested on a group of 10 normal subjects, who were examined bilaterally and the recovered optical images were compared to radiographic breast density. Significantly higher total hemoglobin and water were estimated in the high density relative to low density groups. One patient with invasive ductal carcinoma was also examined and the cancer region was characterized as having a contrast ratio of 1.4 in total hemoglobin and 1.2 in water.
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Registered trials
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