ArticleCritical care research and practice2016
Accuracy of Transcutaneous Carbon Dioxide Measurement in Premature Infants.
Article in Critical care research and practice, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed.
- Physiological effects of high-flow nasal cannula therapy in preterm infants.Archives of disease in childhood. Fetal and neonatal edition · 2020Trial
- Correlation of Transcutaneous pCOPediatric pulmonology · 2026Article
- Transcutaneous carbon dioxide monitoring: ready to be standard of care?Pediatric research · 2026Article
- Accuracy of noninvasive transcutaneous carbon dioxide monitoring in preterm neonates and very low birth weight infants compared with larger neonates.Frontiers in pediatrics · 2026Article
- Patient characteristics, vital signs and tcpCOFrontiers in pediatrics · 2026Article
- Transcutaneous COJournal of clinical medicine · 2023Article
- Validation of a new combined transcutaneous tcPCOPaediatric anaesthesia · 2022Observational
- Non-invasive carbon dioxide monitoring in neonates: methods, benefits, and pitfalls.Journal of perinatology : official journal of the California Perinatal Association · 2021Review
- Feasibilty of Transcutaneous pCOFrontiers in pediatrics · 2020Article
- Delayed cord clamping is associated with improved dynamic cerebral autoregulation and decreased incidence of intraventricular hemorrhage in preterm infants.Journal of applied physiology (Bethesda, Md. : 1985) · 2019Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background. In premature infants, maintaining blood partial pressure of carbon dioxide (pCO2) value within a narrow range is important to avoid cerebral lesions. The aim of this study was to assess the accuracy of a noninvasive transcutaneous method (TcpCO2), compared to blood partial pressure of carbon dioxide (pCO2). Methods. Retrospective observational study in a tertiary neonatal intensive care unit. We analyzed the correlation between blood pCO2 and transcutaneous values and the accuracy between the trends of blood pCO2 and TcpCO2 in all consecutive premature infants born at <33 weeks' gestational age. Results. 248 infants were included (median gestational age: 29 + 5 weeks and median birth weight: 1250 g), providing 1365 pairs of TcpCO2 and blood pCO2 values. Pearson's R correlation between these values was 0.58. The mean bias was -0.93 kPa with a 95% confidence limit of agreement of -4.05 to +2.16 kPa. Correlation between the trends of TcpCO2 and blood pCO2 values was good in only 39.6%. Conclusions. In premature infants, TcpCO2 was poorly correlated to blood pCO2, with a wide limit of agreement. Furthermore, concordance between trends was equally low. We warn about clinical decision-making on TcpCO2 alone when used as continuous monitoring.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.