Evidence map›Paper›PMID 27375765›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2016

The Effect of Photoluminescence of Bioceramic Irradiation on Middle Cerebral Arterial Occlusion in Rats.

Lei Zhang, Paul Chan, Zhong-Min Liu, Ling-Ling Hwang, Kuo-Chi Lin, Wing P Chan, Ting-Kai Leung, Cheuk Sing Choy

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Lei ZhangDepartment of Radiology, Shanghai East Hospital, Tongji University, 1800 Yantai Road, Shanghai 200123, China.
Paul ChanDivision of Cardiology, Department of Internal Medicine, Wan Fang Hospital, Taipei Medical University, No. 111, Sec. 3, Singlong Road, Taipei 116, Taiwan.
Zhong-Min LiuDepartment of Cardiac Surgery, Shanghai East Hospital, Tongji University, 1800 Yantai Road, Shanghai 200123, China.
Ling-Ling HwangDepartment of Physiology, Taipei Medical University, No. 250, Wu Hsing Street, Taipei 110, Taiwan.
Kuo-Chi LinDepartment of Diagnostic Radiology, Cathay General Hospital, 280 Renai Road, Sec. 4, Taipei 106, Taiwan.
Wing P ChanDepartment of Radiology, Wan Fang Hospital, Taipei Medical University, No. 111, Sec. 3, Singlong Road, Taipei 116, Taiwan.
Ting-Kai LeungDepartment of Radiology, Wan Fang Hospital, Taipei Medical University, No. 111, Sec. 3, Singlong Road, Taipei 116, Taiwan; Graduate Institute of Biomedical Materials and Tissue Engineering, College of Medical Engineering, Taipei Medical University, No. 250, Wu Hsing Street, Taipei 110, Taiwan; Department of Radiology, Taipei Hospital, Ministry of Health and Welfare, No. 127 Su Yuan Road, Hsinchuang District, New Taipei City 242-13, Taiwan.
Cheuk Sing ChoyDepartment of Emergency, Min-Sheng General Hospital, 168 Ching-Kuo Road, Taoyuan 330, Taiwan.
Taipei Medical University · TWShanghai East Hospital · CNCathay General Hospital · TWMin Sheng General Hospital · TWWan Fang Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of this study is to determine the possible effect of photoluminescence of bioceramic (PLB) on ischemic cerebral infarction (stroke), by using an animal model of transient middle cerebral artery occlusion (MCAO). Sprague-Dawley rats were used to induce MCAO to block the origin of the left MCAO; three months later, the positive chronic stroke rats were selected by running tunnel maze; the MCAO rats with significant chronic stroke and neurological defects were used for treadmill experiments with varying speed settings to test their capability for restoration after muscular fatigue under conditions of with and without PLB irradiation. As a result, PLB irradiation could improve exercise completion rate and average running speed during slow and fast treadmill settings. After PLB irradiation, the selected MCAO rats successfully completed all the second-round treadmill exercises at the maximum speed setting, and they had better restoration from muscular fatigue. An in vitro cell study on astrocytes of rats by bioceramic irradiation further demonstrated increased intracellular nitric oxide. To explain these results, we suggest that cortical brain stimulation of microcirculation and enhancement of peripheral muscular activity are the main causes of the improved exercise performance in MCAO rats by PLB.

Identifiers

PMID27375765
PMCPMC4914731
OpenAlexW2418844414

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.