Evidence map›Paper›PMID 27375696›Full record

ArticlePakistan journal of medical sciences

Frequency of minimal hepatic encepalopathy in illeterate patients with compensated cirrhosis.

Bader Faiyaz Zuberi, Haris Alvi, Faisal Faiyaz Zuberi, Tazeen Rasheed, Zunaira Nawaz, Fatima-Tuz-Zohra

Registry-linked trialAbstract read
In one paragraph

Article in Pakistan journal of medical sciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04436601 (Effect of Polyethylene Glycol Versus Lactulose on Hepatic Encephalopathy in Patients With Liver Cirrhosis; a Randomized Clinical Trial), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04436601 phase4unknown statusnot on this map

Effect of Polyethylene Glycol Versus Lactulose on Hepatic Encephalopathy in Patients With Liver Cirrhosis; a Randomized Clinical Trial (PEGHE Trial)

TypeinterventionalSponsorAga Khan UniversityRan2020 to 2023Enrolled102ConditionsHepatic EncephalopathyArmsPolyethylene Glycols, Lactulose
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Bader Faiyaz ZuberiProf. Bader Faiyaz Zuberi, FCPS. Department of Medicine, Dow University of Health Sciences, Karachi, Pakistan.
Haris AlviDr. Haris Alvi, FCPS. Department of Medicine, Dow University of Health Sciences, Karachi, Pakistan.
Faisal Faiyaz ZuberiDr. Faisal Faiyaz Zuberi, FCPS. Department of Pulmonology, Dow University of Health Sciences, Karachi, Pakistan.
Tazeen RasheedDr. Tazeen Rasheed, FCPS. Department of Medicine, Dow University of Health Sciences, Karachi, Pakistan.
Zunaira NawazDr. Zunaira Nawaz, FCPS. Department of Medicine, Dow University of Health Sciences, Karachi, Pakistan.
Fatima-Tuz-ZohraDr. Fatima-tuz-Zohra, MBBS. Department of Medicine, Dow University of Health Sciences, Karachi, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine frequency of Minimal Hepatic Encephalopathy in illiterate patients with compensated cirrhosis.

methodsIlliterate patients with compensated cirrhosis with F4 Score on Shear-wave Elastography were selected for study after informed consent. Sample size was estimated at 106. Selected patients were subjected to two tests for detection of MHE, Number Connection Test A and Block Design Test. Patients taking ≥ 30 seconds were labelled as Positive for MHE.

resultOut of 110 selected patients 10.9% were alcoholics and in 8.2% of patients no hepatic virus infection was detected. HCV was positive in 48.2% patients while HBV was positive in 13.6% of patients. MHE was detected in 72 (65.5%) of patients. Major differences were found in MHE Stage II & III by two tests. Over all BDT detected more cases and gave higher Staging in Stage II & III as compared to NCT-A test.

conclusionMinimal Hepatic Encephalopathy (MHE) could be detected in illiterate patients using NCT-A and BDT Tests.

Indexed as

Compensated CirrhosisIlletrateMinimal Hepatic Encephalopathy

Identifiers

PMID27375696
PMCPMC4928405

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Registered trials

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