Evidence map›Paper›PMID 27375684›Full record

ArticlePakistan journal of medical sciences

Cardiovascular risk score in Rheumatoid Arthritis.

Abrar Ahmed Wagan, Tafazzul E Haque Mahmud, Aflak Rasheed, Zafar Ali Zafar, Ata Ur Rehman, Amjad Ali

Abstract read
In one paragraph

Article in Pakistan journal of medical sciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Abnormal Glucose Metabolism in Rheumatoid Arthritis.BioMed research international · 2017
    Review
  5. IL-6 Promotes IsletJournal of diabetes research · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Abrar Ahmed WaganDr. Abrar Ahmed Wagan, FCPS (Medicine). Department of Rheumatology, Sheikh Zayed Federal Post Graduate Institute, Lahore, Pakistan.
Tafazzul E Haque MahmudDr. Tafazzul E Haque Mahmud, MRCP, FRCP. Department of Rheumatology, Sheikh Zayed Federal Post Graduate Institute, Lahore, Pakistan.
Aflak RasheedDr. Aflak Rasheed, FCPS (Medicine) FCPS(Rheumatology). Department of Rheumatology, Sheikh Zayed Federal Post Graduate Institute, Lahore, Pakistan.
Zafar Ali ZafarDr. Zafar Ali Zafar, FCPS (Medicine). Department of Rheumatology, Sheikh Zayed Federal Post Graduate Institute, Lahore, Pakistan.
Ata Ur RehmanDr. Ata Ur Rehman, FCPS (Medicine). Department of Rheumatology, Sheikh Zayed Federal Post Graduate Institute, Lahore, Pakistan.
Amjad AliDr. Amjad Ali, MBBS. Department of Rheumatology, Sheikh Zayed Federal Post Graduate Institute, Lahore, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine the 10-year Cardiovascular risk score with QRISK-2 and Framingham risk calculators in Rheumatoid Arthritis and Non Rheumatoid Arthritis subjects and asses the usefulness of QRISK-2 and Framingham calculators in both groups.

methodsDuring the study 106 RA and 106 Non RA patients age and sex matched participants were enrolled from outpatient department. Demographic data and questions regarding other study parameters were noted. After 14 hours of fasting 5 ml of venous blood was drawn for Cholesterol and HDL levels, laboratory tests were performed on COBAS c III (ROCHE). QRISK-2 and Framingham risk calculators were used to get individual 10-year CVD risk score.

resultsIn this study the mean age of RA group was (45.1±9.5) for Non RA group (43.7±8.2), with female gender as common. The mean predicted 10-year score with QRISK-2 calculator in RA group (14.2±17.1%) and Non RA group was (13.2±19.0%) with (p-value 0.122). The 10-year score with Framingham risk score in RA group was (12.9±10.4%) and Non RA group was (8.9±8.7%) with (p-value 0.001). In RA group QRISK-2 (24.5%) and FRS (31.1%) cases with predicted score were in higher risk category. The maximum agreement scores between both calculators was observed in both groups (Kappa = 0.618 RA Group; Kappa = 0.671 Non RA Group).

conclusionQRISK-2 calculator is more appropriate as it takes RA, ethnicity, CKD, and Atrial fibrillation as factors in risk assessment score.

Indexed as

AF: Atrial FibrillationBMI: Body Mass IndexCHOL: CholesterolCKD: Chronic kidney diseasesCVD: Cardiovascular diseasesCVD risk scoreDM: Diabetes MellitusFramingham risk calculatorHDL: High Density LipoproteinQRISK-2 calculatorRA: Rheumatoid ArthritisRheumatoid Arthritis

Identifiers

PMID27375684
PMCPMC4928393

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.