ArticleFrontiers in behavioral neuroscience2016
Repetitive Transcranial Direct Current Stimulation Induced Excitability Changes of Primary Visual Cortex and Visual Learning Effects-A Pilot Study.
Article in Frontiers in behavioral neuroscience, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 47 citations in OpenAlex.
- Transcranial direct current stimulation of the prefrontal and visual cortices diversely affects early and late perceptual learning.Brain and behavior · 2024Trial
- Visual motion perception improvements following direct current stimulation over V5 are dependent on initial performance.Experimental brain research · 2020Trial
- Trial
- Frequency-dependent photic modulation of wakeful consolidation in visual learning.Nature communications · 2025Article
- Induction of excitatory brain state governs plastic functional changes in visual cortical topology.Brain structure & function · 2024Review
- Enhancing visual perceptual learning using transcranial electrical stimulation: Transcranial alternating current stimulation outperforms both transcranial direct current and random noise stimulation.Journal of vision · 2023Article
- Can visual cortex non-invasive brain stimulation improve normal visual function? A systematic review and meta-analysis.Frontiers in neuroscience · 2023Review
- Cortical excitability in human somatosensory and visual cortex: implications for plasticity and learning - a minireview.Frontiers in human neuroscience · 2023Review
- Recognizing intertwined patterns using a network of spiking pattern recognition platforms.Scientific reports · 2022Article
- Enhancement of visual perception by combining transcranial electrical stimulation and visual perceptual training.Medical review (2021) · 2022Review
- High-definition transcranial direct current stimulation of the left middle temporal complex does not affect visual motion perception learning.Frontiers in neuroscience · 2022Article
- Functional Interactions between Sensory and Memory Networks for Adaptive Behavior.Cerebral cortex (New York, N.Y. : 1991) · 2021Article
- Offline transcranial direct current stimulation improves the ability to perceive crowded targets.Journal of vision · 2021Article
- Effects of High-Definition Transcranial Direct Current Stimulation Over the Left Fusiform Face Area on Face View Discrimination Depend on the Individual Baseline Performance.Frontiers in neuroscience · 2021Article
- Visual cortex cTBS increases mixed percept duration while a-tDCS has no effect on binocular rivalry.PloS one · 2021Article
- Parallel modulation of intracortical excitability of somatosensory and visual cortex by the gonadal hormones estradiol and progesterone.Scientific reports · 2020Article
- Excitation of the Pre-frontal and Primary Visual Cortex in Response to Transcorneal Electrical Stimulation in Retinal Degeneration Mice.Frontiers in neuroscience · 2020Article
- Does Transcranial Direct Current Stimulation (tDCS) Improve Disgust Regulation Through Imagery Rescripting?Frontiers in human neuroscience · 2019Article
- The effect of LTP- and LTD-like visual stimulation on modulation of human orientation discrimination.Scientific reports · 2018Article
- GABA, not BOLD, reveals dissociable learning-dependent plasticity mechanisms in the human brain.eLife · 2018Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Studies on noninvasive motor cortex stimulation and motor learning demonstrated cortical excitability as a marker for a learning effect. Transcranial direct current stimulation (tDCS) is a non-invasive tool to modulate cortical excitability. It is as yet unknown how tDCS-induced excitability changes and perceptual learning in visual cortex correlate. Our study aimed to examine the influence of tDCS on visual perceptual learning in healthy humans. Additionally, we measured excitability in primary visual cortex (V1). We hypothesized that anodal tDCS would improve and cathodal tDCS would have minor or no effects on visual learning. Anodal, cathodal or sham tDCS were applied over V1 in a randomized, double-blinded design over four consecutive days (n = 30). During 20 min of tDCS, subjects had to learn a visual orientation-discrimination task (ODT). Excitability parameters were measured by analyzing paired-stimulation behavior of visual-evoked potentials (ps-VEP) and by measuring phosphene thresholds (PTs) before and after the stimulation period of 4 days. Compared with sham-tDCS, anodal tDCS led to an improvement of visual discrimination learning (p < 0.003). We found reduced PTs and increased ps-VEP ratios indicating increased cortical excitability after anodal tDCS (PT: p = 0.002, ps-VEP: p = 0.003). Correlation analysis within the anodal tDCS group revealed no significant correlation between PTs and learning effect. For cathodal tDCS, no significant effects on learning or on excitability could be seen. Our results showed that anodal tDCS over V1 resulted in improved visual perceptual learning and increased cortical excitability. tDCS is a promising tool to alter V1 excitability and, hence, perceptual visual learning.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.