Evidence map›Paper›PMID 27375299›Full record

ReviewMacromolecules2016

Biosynthetic Polymers as Functional Materials.

Andrea S Carlini, Lisa Adamiak, Nathan C Gianneschi

Abstract readReview
In one paragraph

Review in Macromolecules, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. 3D printed microneedles: revamping transdermal drug delivery systems.Drug delivery and translational research · 2025
    Review
  5. Review
  6. Smart Hydrogels for Tissue Regeneration.Macromolecular bioscience · 2024
    Review
  7. Review
  8. Article
  9. Review
  10. Article
  11. Hydrogel Formation with Enzyme-Responsive Cyclic Peptides.Methods in molecular biology (Clifton, N.J.) · 2022
    Article
  12. Review
  13. Article
  14. Article
  15. POLYMERIC BIOMATERIALS FOR SCAFFOLD-BASED BONE REGENERATIVE ENGINEERING.Regenerative engineering and translational medicine · 2019
    Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Andrea S CarliniDepartment of Chemistry and Biochemistry, University of California, San Diego , La Jolla, California 92093, United States.
Lisa AdamiakDepartment of Chemistry and Biochemistry, University of California, San Diego , La Jolla, California 92093, United States.
Nathan C GianneschiDepartment of Chemistry and Biochemistry, University of California, San Diego , La Jolla, California 92093, United States.

Funding

Programming Pharmacokinetics in Vivo via In Situ Switching of Nanoscale ParticleDP2OD008724 · OD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GIANNESCHI, NATHAN CLAUDE · 2011 to 2011
$2.3M
Autonomously Assembling Nanomaterial Scaffolds for Treating Myocardial InfarctionR01HL117326 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CHRISTMAN, KAREN L, GIANNESCHI, NATHAN CLAUDE · 2012 to 2016
$1.9M
EDAPT: Enzyme-Directed Assembly of Particle TheranosticsR01EB011633 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI HALL, DAVID J · 2011 to 2014
$1.3M
NHLBI NIH HHS R01 HL117326NIBIB NIH HHS R01 EB011633NIH HHS DP2 OD008724
6 · The paper itself

Abstract

The synthesis of functional polymers encoded with biomolecules has been an extensive area of research for decades. As such, a diverse toolbox of polymerization techniques and bioconjugation methods has been developed. The greatest impact of this work has been in biomedicine and biotechnology, where fully synthetic and naturally derived biomolecules are used cooperatively. Despite significant improvements in biocompatible and functionally diverse polymers, our success in the field is constrained by recognized limitations in polymer architecture control, structural dynamics, and biostabilization. This Perspective discusses the current status of functional biosynthetic polymers and highlights innovative strategies reported within the past five years that have made great strides in overcoming the aforementioned barriers.

Identifiers

PMID27375299
PMCPMC4928144

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.