SynthesisJournal of cardiac failure2016
What Are Effective Program Characteristics of Self-Management Interventions in Patients With Heart Failure? An Individual Patient Data Meta-analysis.
Synthesis in Journal of cardiac failure, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
60 citing papers in PubMed, 5 syntheses or guidelines pooled it, 134 citations in OpenAlex.
- Remote patient monitoring in heart failure: A comprehensive meta-analysis of effective programme components for hospitalization and mortality reduction.European journal of heart failure · 2025Pooled it
- Social network interventions to support cardiac rehabilitation and secondary prevention in the management of people with heart disease.The Cochrane database of systematic reviews · 2023Pooled it
- Optimal effectiveness of heart failure management - an umbrella review of meta-analyses examining the effectiveness of interventions to reduce (re)hospitalizations in heart failure.Heart failure reviews · 2022Pooled it
- Electronic Health Self-Management Interventions for Patients With Chronic Kidney Disease: Systematic Review of Quantitative and Qualitative Evidence.Journal of medical Internet research · 2019Pooled it
- Self-Care for the Prevention and Management of Cardiovascular Disease and Stroke: A Scientific Statement for Healthcare Professionals From the American Heart Association.Journal of the American Heart Association · 2017Guideline
- Effectiveness of an Intervention to Improve Guideline-Directed Medications for Patients With Acute Heart Failure: A Randomized Clinical Trial.Journal of the American Heart Association · 2026Trial
- Effectiveness and Cost-effectiveness of an Empowerment-Based Self-care Education Program on Health Outcomes Among Patients With Heart Failure: A Randomized Clinical Trial.JAMA network open · 2022Trial
- The value of social practice theory for implementation science: learning from a theory-based mixed methods process evaluation of a randomised controlled trial.BMC medical research methodology · 2020Trial
- Trial
- Global Trends in Heart Failure Self-Care Research: A Bibliometric and Visual Analysis.Healthcare (Basel, Switzerland) · 2026Review
- Seven-day ECG Holter vs. 14-day event Holter in the detection of life-threatening ventricular arrhythmias, new atrial fibrillation, and silent ischemia among heart failure patients from social exclusion regions.Cardiology journal · 2026Article
- Congestion assessment using a self-supervised contrastive learning-derived risk index in patients with congestive heart failure (CONAN): protocol and design of a prospective cohort study.European heart journal. Digital health · 2025Article
- Efficacy of Nurse-Led and Multidisciplinary Self-Management Programmes for Heart Failure with Reduced Ejection Fraction: An Umbrella Systematic Review.Biomedicines · 2025Review
- Quality of life in heart failure. The heart of the matter. A scientific statement of the Heart Failure Association and the European Association of Preventive Cardiology of the European Society of Cardiology.European journal of heart failure · 2025Article
- Historical Gaps in the Integration of Patient-Centric Self-Management Components in HFrEF Interventions: An Umbrella Narrative Review.Journal of clinical medicine · 2025Review
- Self-Study-Based Informed Decision-Making Tool for Empowerment of Treatment Adherence Among Chronic Heart Failure Patients-A Pilot Study.Healthcare (Basel, Switzerland) · 2025Article
- A Cross-Sectoral Telemedicine Network (sekTOR-HF) for Patients with Heart Failure.Journal of clinical medicine · 2025Article
- Chronic Heart Failure and Coronary Artery Disease: Pharmacological Treatment and Cardiac Rehabilitation.Medicina (Kaunas, Lithuania) · 2025Review
- Cardiomeds, an mHealth App for Self-Management to Support Swiss Patients With Heart Failure: 2-Stage Mixed Methods Usability Study.JMIR formative research · 2025Article
- Article
Corrections and comments
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Authors and funding
25 authors at 18 institutions in 9 countries.
Funding
Abstract
backgroundTo identify those characteristics of self-management interventions in patients with heart failure (HF) that are effective in influencing health-related quality of life, mortality, and hospitalizations. METHODS AND
resultsRandomized trials on self-management interventions conducted between January 1985 and June 2013 were identified and individual patient data were requested for meta-analysis. Generalized mixed effects models and Cox proportional hazard models including frailty terms were used to assess the relation between characteristics of interventions and health-related outcomes. Twenty randomized trials (5624 patients) were included. Longer intervention duration reduced mortality risk (hazard ratio 0.99, 95% confidence interval [CI] 0.97-0.999 per month increase in duration), risk of HF-related hospitalization (hazard ratio 0.98, 95% CI 0.96-0.99), and HF-related hospitalization at 6 months (risk ratio 0.96, 95% CI 0.92-0.995). Although results were not consistent across outcomes, interventions comprising standardized training of interventionists, peer contact, log keeping, or goal-setting skills appeared less effective than interventions without these characteristics.
conclusionNo specific program characteristics were consistently associated with better effects of self-management interventions, but longer duration seemed to improve the effect of self-management interventions on several outcomes. Future research using factorial trial designs and process evaluations is needed to understand the working mechanism of specific program characteristics of self-management interventions in HF patients.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.