ArticleNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology2016
Elevated Dopamine D
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In one paragraph
Article in Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 4 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 4 pooled it
2.7field-weighted citation impact, top 11% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 4 syntheses or guidelines pooled it, 60 citations in OpenAlex.
- Brain dopamine receptor system is not altered in obesity: Bayesian and frequentist meta-analyses.Human brain mapping · 2023Pooled it
- Effects of bariatric surgery and dietary interventions for obesity on brain neurotransmitter systems and metabolism: A systematic review of positron emission tomography (PET) and single-photon emission computed tomography (SPECT) studies.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2023Pooled it
- The historical progression of positron emission tomography research in neuroendocrinology.Frontiers in neuroendocrinology · 2023Pooled it
- Striatal dopamine D2-like receptors availability in obesity and its modulation by bariatric surgery: a systematic review and meta-analysis.Scientific reports · 2023Pooled it
- Kappa opioid receptor availability correlates with depressive symptom burden in chronic migraine: a preliminary investigation.The journal of headache and pain · 2026Article
- The Change of Dopamine Transporter After Glucose Loading Is Associated With an Individual's Attitude Toward Sweet Foods in Healthy Young Males.Human brain mapping · 2025Article
- Effects of Age and BMI on Histamine H3 Receptor Availability in Healthy Humans.Molecular imaging and biology · 2025Article
- PET/fMRI demonstrates that bariatric surgery may reverse striatal dopaminergic dysfunction in women with obesity.Communications medicine · 2025Article
- Investigating dopaminergic abnormalities in schizophrenia and first-episode psychosis with normative modelling and multisite molecular neuroimaging.Molecular psychiatry · 2025Article
- Striatal dopamine tone is positively associated with adiposity in humans as determined by PET using dual dopamine type-2 receptor antagonist tracers.Molecular psychiatry · 2025Article
- Central dopamine receptors: Radiotracers unveiling the Role of dopaminergic tone in obesity.Journal of molecular medicine (Berlin, Germany) · 2025Review
- Operant Training for Highly Palatable Food Alters Translating Messenger RNA in Nucleus Accumbens DBiological psychiatry · 2024Article
- Nucleus accumbens D1- and D2-expressing neurons control the balance between feeding and activity-mediated energy expenditure.Nature communications · 2024Article
- Intense exercise increases dopamine transporter and neuromelanin concentrations in the substantia nigra in Parkinson's disease.NPJ Parkinson's disease · 2024Article
- Molecular Imaging of Central Dopamine in Obesity: A Qualitative Review across Substrates and Radiotracers.Brain sciences · 2022Review
- Neuroimaging and modulation in obesity and diabetes research: 10th anniversary meeting.International journal of obesity (2005) · 2022Review
- NRM 2021 Abstract Booklet.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2021Article
- First-in-Human Assessment ofJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2021Article
- Dopamine DDrug and alcohol dependence · 2021Article
- The Neurobiology of Binge-eating Disorder Compared with Obesity: Implications for Differential Therapeutics.Clinical therapeutics · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 1 institution in 1 country.
Edward C GaiserDepartment of Radiology and Biomedical Imaging, Yale University, New Haven, CT, USA.
Jean-Dominique GallezotDepartment of Radiology and Biomedical Imaging, Yale University, New Haven, CT, USA.ORCID 0000-0003-0399-8374
Patrick D WorhunskyDepartment of Radiology and Biomedical Imaging, Yale University, New Haven, CT, USA.
Ania M JastreboffDepartment of Internal Medicine, Endocrinology, Yale University, New Haven, CT, USA.
Brian PittmanDepartment of Psychiatry, Yale University, New Haven, CT, USA.
Lauren KantrovitzDepartment of Psychiatry, Yale University, New Haven, CT, USA.
Gustavo A AngaritaDepartment of Psychiatry, Yale University, New Haven, CT, USA.
Kelly P CosgroveDepartment of Radiology and Biomedical Imaging, Yale University, New Haven, CT, USA.
Marc N PotenzaDepartment of Psychiatry, Yale University, New Haven, CT, USA.
Robert T MalisonDepartment of Psychiatry, Yale University, New Haven, CT, USA.
Richard E CarsonDepartment of Radiology and Biomedical Imaging, Yale University, New Haven, CT, USA.
David MatuskeyDepartment of Radiology and Biomedical Imaging, Yale University, New Haven, CT, USA.
Yale University · US
Funding
Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9MYale Diabetes Research CenterP30DK045735 · NIDDK · YALE UNIVERSITY · PI Kevan C Herold, GERALD I SHULMAN · 1993 to 2026
$44.0MYale University Clinical and Translational Science Award ProgramUL1TR000142 · NCATS · YALE UNIVERSITY · PI SHERWIN, ROBERT S · 2012 to 2015
$31.8MSUBSTANCE ABUSEK12DA000167 · NIDA · YALE UNIVERSITY · PI STEPHANIE S O'MALLEY, Marc N Potenza · 1991 to 2026
$17.7MClinical Neuroscience Research Training Program in PsychiatryT32MH019961 · NIMH · YALE UNIVERSITY · PI Christopher John Pittenger · 1996 to 2026
$5.9MNeuroimaging Sciences Training ProgramT32DA022975 · NIDA · YALE UNIVERSITY · PI Graeme F Mason, Rajita Sinha · 2007 to 2026
$5.7MTranslational Research of Cocaine, Striatum, and ImpulsivitiesP20DA027844 · NIDA · YALE UNIVERSITY · PI TAYLOR, JANE R · 2010 to 2013
$3.6MPatient-Oriented Research and Mentoring in the Translational Neurobiology/GeneticK24DA017899 · NIDA · YALE UNIVERSITY · PI MALISON, ROBERT T · 2007 to 2012
$827kImaging Genetics in Tobacco SmokersK02DA031750 · NIDA · YALE UNIVERSITY · PI COSGROVE, KELLY P. · 2012 to 2016
$634kDBH, D2High and Cocaine Paranoia/Aversion: A [11C]PHNO PET StudyR03DA027456 · NIDA · YALE UNIVERSITY · PI MALISON, ROBERT T · 2009 to 2010
$420kNCATS NIH HHS UL1 TR000142NCATS NIH HHS UL1 TR001863NIDA NIH HHS K02 DA031750NIDA NIH HHS K12 DA000167NIDA NIH HHS K24 DA017899NIDA NIH HHS P20 DA027844NIDA NIH HHS R03 DA027456NIDA NIH HHS T32 DA022975NIDDK NIH HHS P30 DK045735NIMH NIH HHS T32 MH019961
Abstract
Most prior work with positron emission tomography (PET) dopamine subtype 2/3 receptor (D
Indexed as
Positron-Emission TomographyAdultBody Mass IndexBrainCase-Control StudiesCohort StudiesDopamine AgonistsFemaleHumansMaleMiddle AgedObesityOxazinesReceptors, Dopamine D2Receptors, Dopamine D3Young AdultDopamine AgonistsDRD2 protein, humannaxagolideOxazinesReceptors, Dopamine D2Receptors, Dopamine D3
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Textmetadata
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.