Evidence map›Paper›PMID 27374126›Full record

ReviewInfectious diseases of poverty2016

Critical analysis of molluscicide application in schistosomiasis control programs in Brazil.

Pmz Coelho, R L Caldeira

Open access · goldAbstract readReview
In one paragraph

Review in Infectious diseases of poverty, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 1 pooled it
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 1 synthesis or guideline pooled it, 84 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Molluscicidal and Schistosomicidal Activities of 2-(1Pharmaceuticals (Basel, Switzerland) · 2025
    Article
  6. Article
  7. Article
  8. Molluscicidal activity of sodium hypochlorite againstParasite epidemiology and control · 2023
    Article
  9. Review
  10. Article
  11. Effect ofMolecules (Basel, Switzerland) · 2022
    Article
  12. Transmission potential of human schistosomes can be driven by resource competition among snail intermediate hosts.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  13. Article
  14. Current Status for Controlling the Overlooked Caprine Fasciolosis.Animals : an open access journal from MDPI · 2021
    Review
  15. Interventions can shift the thermal optimum for parasitic disease transmission.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Pmz CoelhoResearch group of Schistosoma mansoni Biology and Its Interaction with the Host, René Rachou Institute, Oswaldo Cruz Foundation-Minas Gerais, 30190-002, Belo Horizonte, MG, Brazil.
R L CaldeiraResearch group of Medical Helminthology and Malacology, René Rachou Institute, Oswaldo Cruz Foundation-Minas Gerais, 30190-002, Belo Horizonte, MG, Brazil. caldeira@cpqrr.fiocruz.br.
Fundação Oswaldo Cruz · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In Brazil, Biomphalaria glabrata, B. tenagophila, and B. straminea are naturally infected by the trematode Schistosoma mansoni, the causative agent of schistosomiasis. Despite decades of governmental efforts through official control programs, schistosomiasis remains an important public health problem in the country: thousands of people are infected with the trematode each year and millions live in endemic areas. The World Health Organization recommends using a combination of molluscicide (niclosamide) and mass chemotherapy to control the transmission of schistosomiasis, with this treatment successfully reducing the morbidity of the disease. In the past, niclosamide has been used in official schistosomiasis control programs in Brazil. However, as B. glabrata recolonizes even after molluscicide application, the use of molluscicides has gradually decreased in the country until they were discontinued in 2002, mainly due to the rising global pressure to preserve the environment and the difficulties of obtaining licenses from the Brazilian Ministry of Environment to use toxic substances in aquatic ecosystems. Therefore, the discovery of new molluscicides, which could be more selective to Biomphalaria species and less harmful to the aquatic ecosystem, is necessary. In addition, political efforts to sensitize funders to provide grants for this field of research are required. In this context, this article aims to make a critical analysis of molluscicide application in schistosomiasis control programs in Brazil.

Indexed as

BiomphalariaMolluscacidesNiclosamideAnimalsBrazilCommunicable Disease ControlSchistosoma mansoniSchistosomiasisSpecies SpecificityMolluscacidesNiclosamideBiomphalariaBrazilMolluscicideSchistosoma mansoniSchistosomiasisVector control

Identifiers

PMID27374126
PMCPMC4931695
OpenAlexW2463694689

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.