ArticleJournal of atherosclerosis and thrombosis2016
Reference Values for The Triglyceride to High-Density Lipoprotein Cholesterol Ratio and Non-High-Density Lipoprotein Cholesterol in Korean Children and Adolescents: The Korean National Health and Nutrition Examination Surveys 2007-2013.
Article in Journal of atherosclerosis and thrombosis, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 45 citations in OpenAlex.
- 2017 Clinical practice guidelines for dyslipidemia of Korean children and adolescents.Clinical and experimental pediatrics · 2020Guideline
- 2017 Clinical practice guidelines for dyslipidemia of Korean children and adolescents.Annals of pediatric endocrinology & metabolism · 2020Guideline
- Screening for insulin resistance in children with abdominal obesity: sex-specific performance of TyG index, FGIR, and VAI.Physical activity and nutrition · 2026Article
- Reference intervals for aCL and anti-β2GPI IgAGM antibodies in a large health-inspection population: a foundational study for combined-isotype assay interpretation.Lupus science & medicine · 2026Article
- Age-related insulin resistance changes in children and adolescents and its impact on the accuracy of diagnosis of metabolic syndrome.Annals of pediatric endocrinology & metabolism · 2025Article
- Angiotensinogen M235T Gene Polymorphism and Risk of Ischemic Heart Disease Complication among Patients with Hypertension in the Ethiopian Population.Ethiopian journal of health sciences · 2025Article
- High free sugars, insulin resistance, and low socioeconomic indicators: the hubs in the complex network of non-communicable diseases in adolescents.Diabetology & metabolic syndrome · 2024Article
- Age- and Gender-Specific Reference Intervals for the Fasting Serum Lipid Levels in a Pediatric Population Aged 0-＜15 Years in Nanjing, China.Journal of atherosclerosis and thrombosis · 2024Article
- Importance of Setting Reference Ranges for Serum Lipids by Age or Pubertal Stage in Children and Adolescents.Journal of atherosclerosis and thrombosis · 2024Article
- Factors Affecting Dyslipidemia among Korean Adolescents: An Analysis Using the 8th Korea National Health and Nutrition Examination Survey (2021).Children (Basel, Switzerland) · 2023Article
- Intrapartum Factors Affecting Abnormal Lipid Profiles in Early Postpartum Period.Journal of personalized medicine · 2023Article
- Age-, Sex-, and Puberty-Associated Reference Intervals for Lipid Profile in Iranian Children and Adolescents.International journal of endocrinology · 2023Article
- A Comparative Study of the Triglycerides/HDL Ratio and Pseudocholinesterase Levels in Patients with Bladder Cancer.Diagnostics (Basel, Switzerland) · 2022Article
- A new perspective on cholesterol in pediatric health: association of vitamin D metabolism, respiratory diseases, and mental health problems.Clinical and experimental pediatrics · 2022Article
- Subretinal Drusenoid Deposits and Lower Serum High-Density Lipoprotein Cholesterol Levels Possess Latent Relation to Cardiovascular Disease and Can Be a Feasible Predictor.Computational and mathematical methods in medicine · 2022Article
- Coronary Artery Disease: Optimal Lipoprotein(a) for Survival-Lower Is Better? A Large Cohort With 43,647 Patients.Frontiers in cardiovascular medicine · 2021Article
- Limitations of current screening methods for lipid disorders in Korean adolescents and a proposal for an effective detection method: a nationwide, cross-sectional study.Annals of pediatric endocrinology & metabolism · 2020Article
- Reference values for lipid profile in Iranian children and adolescents: the CASPIAN-V study.Lipids in health and disease · 2020Article
- Macrophage-Based Therapies for Atherosclerosis Management.Journal of immunology research · 2020Review
- Association Between TG-to-HDL-C Ratio and In-Stent Stenosis Under Optical Coherence Tomography Guidance.Journal of medical systems · 2018Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimCholesterol levels vary throughout childhood and adolescence. The aim of the present study was to evaluate and identify age- and gender-specific reference values for serum lipid concentrations including non-high-density lipoprotein cholesterol (non-HDL-C) and the triglyceride to HDL-C ratio (TG/HDL-C ratio) in apparently healthy Korean children and adolescents.
methodsA total of 6197 participants aged 10 to 19 years old from the 2007-2013 Korean National Health and Nutrition Examination Survey were analyzed. Serum lipid concentrations were evaluated according to age and gender.
resultsThe overall mean concentration of non-HDL-C was 105.5±25.6 mg/dL, with a significant gender difference: 103.3±26.1 mg/dL in boys and 107.9±24.7 mg/dL in girls (p=0.028). The median values of non-HDL-C concentrations in boys and girls, respectively, were 111 and 112 mg/dL in the 10-year-old age group, 95 and 103 mg/dL in the 15-year-old age group, and 109 and 103 mg/dL in the 19-year-old age group. The overall mean TG/HDL-C ratio was 1.74±1.22, and there were no significant gender differences: 1.77±1.25 in boys and 1.72±1.22 in girls (p=0.183). The median values of the TG/HDL-C ratio in boys and girls were 1.16 and 1.00 in the 10-year-olds, 1.54 and 0.95 in the 15-year-olds, and 1.74 and 0.84 in the 19-year-olds, respectively.
conclusionsAge- and gender-specific reference values for non-HDL-C and for the TG/HDL-C ratio in children and adolescents could provide valuable information for individualized interpretations of lipid profiles and interventions as well as for strategies to prevent and manage childhood and adolescent dyslipidemia.
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