Evidence map›Paper›PMID 27373206›Full record

SynthesisPreventive medicine2016

Benefits of commercial weight-loss programs on blood pressure and lipids: a systematic review.

Ambereen K Mehta, Ruchi S Doshi, Zoobia W Chaudhry, David K Jacobs, Rachit M Vakil, Clare J Lee, Sara N Bleich, Jeanne M Clark, Kimberly A Gudzune

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Preventive medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Long-term effects of weight-reducing diets in people with hypertension.The Cochrane database of systematic reviews · 2021
    Pooled it
  2. Trial
  3. Review
  4. Observational
  5. Review
  6. Review
  7. Article
  8. Observational
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ambereen K MehtaThe Johns Hopkins Bayview Medical Center, Baltimore, MD, USA.
Ruchi S DoshiThe Johns Hopkins University School of Medicine, Baltimore, MD, USA; The Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Zoobia W ChaudhryThe Johns Hopkins University School of Medicine, Baltimore, MD, USA.
David K JacobsThe University of Maryland School of Medicine, Baltimore, MD, USA.
Rachit M VakilThe Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA; Rutgers Robert Wood Johnson Medical School, Piscataway, NJ, USA.
Clare J LeeThe Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Sara N BleichThe Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Jeanne M ClarkThe Johns Hopkins University School of Medicine, Baltimore, MD, USA; The Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA; The Welch Center for Prevention, Epidemiology, Prevention, and Clinical Research, Baltimore, MD, USA.
Kimberly A GudzuneThe Johns Hopkins University School of Medicine, Baltimore, MD, USA; The Welch Center for Prevention, Epidemiology, Prevention, and Clinical Research, Baltimore, MD, USA. Electronic address: gudzune@jhu.edu.

Funding

Research BaseP30DK072488 · NIDDK · UNIVERSITY OF MARYLAND BALTIMORE · PI MITCHELL, BRAXTON D, TAYLOR, SIMEON I. · 2005 to 2019
$17.3M
Translational Research Enhancement CoreP30DK089502 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI KOVBASNJUK, OLGA · 2011 to 2020
$12.0M
JHU-UMD Diabetes Research CenterP30DK079637 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI AHIMA, REXFORD S. · 2013 to 2017
$9.7M
Institute for Clinical and Translational ResearchTL1TR001078 · NCATS · JOHNS HOPKINS UNIVERSITY · PI FORD, DANIEL ERNEST · 2013 to 2017
$1.9M
Reducing obesity among public housing residents: an ecological approachK23HL116601 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI GUDZUNE, KIMBERLY ANNE · 2013 to 2017
$778k
Racial Disparities in Physician Practice Patterns and Self-Management of ObesityK01HL096409 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI BLEICH, SARA NAOMI · 2009 to 2013
$699k
NCATS NIH HHS TL1 TR001078NHLBI NIH HHS K01 HL096409NHLBI NIH HHS K23 HL116601NIDDK NIH HHS P30 DK072488NIDDK NIH HHS P30 DK079637NIDDK NIH HHS P30 DK089502
6 · The paper itself

Abstract

Our objective was to compare the effect of commercial weight-loss programs on blood pressure and lipids to control/education or counseling among individuals with overweight/obesity. We conducted a systematic review by searching MEDLINE and Cochrane Database of Systematic Reviews from inception to November 2014 and references identified by the programs. We included randomized, controlled trials ≥12weeks in duration. Two reviewers extracted information on study design, interventions, and mean change in systolic blood pressure (SBP), diastolic blood pressure (DBP), low-density lipoprotein cholesterol (LDL-c), high-density lipoprotein cholesterol (HDL-c), triglycerides, and total cholesterol and assessed risk of bias. We included 27 trials. Participants' blood pressure and lipids were normal at baseline in most trials. At 12months, Weight Watchers showed little change in blood pressure or lipid outcomes as compared to control/education (2 trials). At 12months, Atkins' participants had higher HDL-c and lower triglycerides than counseling (4 trials). Other programs had inconsistent effects or lacked long-term studies. Risk of bias was high for most trials of all programs. In conclusion, limited data exist regarding most commercial weight-loss programs' long-term effects on blood pressure and lipids. Clinicians should be aware that Weight Watchers has limited data that demonstrate CVD risk factor benefits relative to control/education. Atkins may be a reasonable option for patients with dyslipidemia. Additional well-designed, long-term trials are needed to confirm these conclusions and evaluate other commercial programs.

Indexed as

Blood PressureCholesterolCommerceHumansObesityPrimary PreventionRisk FactorsWeight Reduction ProgramsCholesterolBlood pressureCholesterolCommercial weight-loss programsRisk factors

Identifiers

PMID27373206
PMCPMC5300307

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.