Evidence map›Paper›PMID 27373108›Full record

SynthesisRomanian journal of ophthalmology

COGAN'S SYNDROME.

Daniela Adriana Iliescu, Cristina Mihaela Timaru, Mehdi Batras, Algerino De Simone, Cornel Stefan

Abstract readSystematic Review
In one paragraph

Synthesis in Romanian journal of ophthalmology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Acute Limb Ischemia in Cogan Syndrome.The American journal of case reports · 2022
    Article
  11. Aortitis Secondary to Cogan's Syndrome: A Rare Cause of Fever of Unknown Origin.European journal of case reports in internal medicine · 2022
    Article
  12. Article
  13. [Interstitial keratitis in a symptom triad].Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft · 2021
    Article
  14. Article
  15. Rare Diseases of the Orbit.Laryngo- rhino- otologie · 2021
    Review
  16. Systemic diseases and the cornea.Experimental eye research · 2021
    Review
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Daniela Adriana Iliescu
Cristina Mihaela Timaru
Mehdi Batras
Algerino De Simone
Cornel Stefan

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe objective of our study was to review the current knowledge on Cogan's syndrome, including etiology, diagnosis and treatment. Systematic review methodology: Relevant publications on Cogan's syndrome from 1945 to 2014 were studied.

conclusionsCogan's syndrome is a rare autoimmune vasculitis, with unknown pathogenesis. Infection was thought to have played a role in the pathogenesis of the disease, but now the autoimmunity hypothesis is considered more likely to be true. Cogan's syndrome is characterized by ocular and audiovestibular symptoms similar to those of Meniere's syndrome. Approximately 70% of the patients have systemic disease, of which vasculitis is considered the pathological mechanism. Corticosteroids are the first line of treatment; multiple immunosuppressive drugs were also used with varying degrees of success. The novelty in the treatment of the disease is tumor necrosis factor (TNF)-alpha-blockers, but more studies are necessary to establish their efficacy.

Indexed as

Cogan SyndromeDiagnosis, DifferentialDrug Therapy, CombinationGlucocorticoidsHumansImmunosuppressive AgentsLabyrinth DiseasesRare DiseasesRomaniaTreatment OutcomeVasculitisGlucocorticoidsImmunosuppressive Agents

Identifiers

PMID27373108
PMCPMC5729811

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.