ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2016
Potential causative agents of acute gastroenteritis in households with preschool children: prevalence, risk factors, clinical relevance and household transmission.
Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.
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Who cites it
26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 43 citations in OpenAlex.
- Transmission pathways and risk factors for sporadic salmonellosis and campylobacteriosis: a source attribution meta-analysis of European case-control studies.Epidemiology and infection · 2025Pooled it
- Does Dientamoeba fragilis cause diarrhea? A systematic review.Parasitology research · 2018Pooled it
- Review
- No evidence of pathogenicity of Dientamoeba fragilis following detection in stools: A case-control study.Parasite (Paris, France) · 2024Article
- Household Transmission of Viral Acute Gastroenteritis Among Participants Within an Integrated Health Care Delivery System, 2014-2016.Open forum infectious diseases · 2023Article
- Treatment ofNew microbes and new infections · 2023Article
- Health of Post-Institutionalized Haitian Children Adopted to the United States.Maternal and child health journal · 2023Article
- Sapovirus Infections in an Australian Community-Based Healthy Birth Cohort During the First 2 Years of Life.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023Article
- A Cross-Sectional Study on the Occurrence of the Intestinal Protist,International journal of molecular sciences · 2022Article
- Molecular Epidemiology of Human Adenovirus, Astrovirus, and Sapovirus Among Outpatient Children With Acute Diarrhea in Chongqing, China, 2017-2019.Frontiers in pediatrics · 2022Article
- Incidence of enterovirus in patients with acute gastroenteritis.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2021Article
- Contribution of Foods and Poor Food-Handling Practices to the Burden of Foodborne Infectious Diseases in France.Foods (Basel, Switzerland) · 2020Article
- Sapovirus: an emerging cause of childhood diarrhea.Current opinion in infectious diseases · 2020Review
- Household presentation of acute gastroenteritis in a primary care sentinel network: retrospective database studies.BMC public health · 2020Article
- Common Gastrointestinal Symptoms and Associated Factors Among Under-5 Children in Rural Dembiya, Northwest Ethiopia: A Community-Based Cross-Sectional Study.Environmental health insights · 2020Article
- Substantial prevalence of enteroparasitesEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2019Article
- Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2019Article
- Review
- Rapid Increase in Carriage Rates of Enterobacteriaceae Producing Extended-Spectrum β-Lactamases in Healthy Preschool Children, Sweden.Emerging infectious diseases · 2018Article
- Article
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Authors and funding
9 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acute gastroenteritis (AGE) morbidity remains high amongst preschool children, posing a significant societal burden. Empirical data on AGE-causing agents is needed to gauge their clinical relevance and identify agent-specific targets for control. We assessed the prevalence, risk factors and association with symptoms for enteropathogens in households with preschool children. A monthly-repeated cross-sectional survey of enteropathogens in households with preschool children was performed. A parent-child pair per household (n = 907 households) provided faecal samples and reported their symptoms and potential risk exposures. Samples were tested by multiplex reverse transcription polymerase chain reaction (RT-PCR) for 19 enteropathogens. Associations were assessed using logistic regression. 28.3 % of children (n = 981) and 15.6 % of parents (n = 971) carried pathogenic bacteria and/or Escherichia coli-associated pathogenicity genes, and 6.5 % and 3.3 % carried viruses, respectively. Giardia lamblia (4.6 % of children, 2.5 % of parents) and Dientamoeba fragilis (36 %, 39 %, respectively) were the main parasites, and were associated with pet exposure. Living in rural areas was associated with carriage of pathogenic E. coli, norovirus I and D. fragilis. Pathogenic E. coli was associated with summertime and livestock exposure. Attending day-care centres increased the risk of carrying norovirus, sapovirus and G. lamblia. Viruses occurred mainly in winter and were associated with AGE symptoms. Child-parent associations were found for bacterial pathogenicity genes, viruses, G. lamblia and D. fragilis. Enteropathogens spread widely in households with preschool children, particularly viruses, which more often cause symptoms. While bacteria predominate during summer and in those exposed to livestock, viruses predominate in wintertime and, like G. lamblia, are widespread amongst day-care centre attendees.
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